龚海鹏 博士

研究员


1993-1997  清华大学生物科学与技术系  学士  
1997-2000   清华大学生物科学与技术系  硕士
2000-2006   约翰霍普金斯大学分子生物物理学  博士
2006-2007   约翰霍普金斯大学分子生物物理学  博士后
2007-2009   芝加哥大学生物化学和分子生物学  博士后
2009-2014   清华大学生命学院  助理教授
2015-至今    清华大学生命学院  副教授

●  研究兴趣、领域:


1. 发展计算机算法根据氨基酸序列预测蛋白质三维结构
2. 发展分子动力学模拟的新方法用于定量分析生物大分子的大尺度构象变化

 

●  代表性论文:


1. Wenzhi Mao#, Wenze Ding, Yaoguang Xing, and Haipeng Gong*, “AmoebaContact and GDFold as a pipeline for rapid de novo protein structure prediction”, Nature Machine Intelligence, 2: 25-33, 2020.
2. Tong Wang#, Yanhua Qiao, Wenze Ding, Wenzhi Mao, Yaoqi Zhou*, and Haipeng Gong*, “Improved fragment sampling for ab initio protein structure prediction using deep neural networks”, Nature Machine Intelligence, 1: 347-355, 2019.
3. Wenze Ding#, Wenzhi Mao#, Di Shao#, Wenxuan Zhang, and Haipeng Gong*, “DeepConPred2: an improved method for the prediction of protein residue contacts”, Computational and Structural Biotechnology Journal, 16: 503-510, 2018.
4. Wenzhi Mao#, Tong Wang, Wenxuan Zhang, and Haipeng Gong*, “Identification of residue pairing in interacting β-strands from a predicted residue contact map”, BMC Bioinformatics, 19(1): 146, 2018.
5. Juanrong Zhang#, Wenzhi Mao#, Yanhui Ren#, Rui-Ning Sun, Nieng Yan*, and Haipeng Gong*, “Simulating the ion permeation and ion selection for a eukaryotic voltage-gated sodium channel NavPaS”, Protein & Cell, 9(6): 580-585, 2018.
6. Meng Ke#, Yafei Yuan, Xin Jiang, Nieng Yan*, and Haipeng Gong*, “Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE”, PLoS Computational Biology, 13(6): e1005603, 2017.
7. Dapeng Xiong#, Jianyang Zeng*, and Haipeng Gong*, “A deep learning framework for improving long-range residue-residue contact prediction using a hierarchical strategy”, Bioinformatics, 33(17): 2675-2683, 2017.
8. Ruining Sun# and Haipeng Gong*, “Simulating the activation of voltage sensing domain for a voltage-gated sodium channel using polarizable force field”, Journal of Physical Chemistry Letters, 8: 901-908, 2017.
9. Tong Wang#, Yuedong Yang, Yaoqi Zhou, and Haipeng Gong*, “LRFragLib: an effective algorithm to identify fragments for de novo protein structure prediction”, Bioinformatics, 33(5): 677-684, 2017.
10. Yufeng Liu#, Meng Ke, and Haipeng Gong*, “Protonation of Glu135 facilitates the outward-to-inward structural transition of fucose transporter”, Biophysical Journal, 109(3): 542-551, 2015.

●  联系方式:

Email: hgong@tsinghua.edu.cn
Website: http://structpred.life.tsinghua.edu.cn