Shanjin HUANG     Ph.D.

Principal Investigator

Education
1992~1996  B.S., Zhejiang Agricultural University, Zhejiang Province, P.R. China
    Major: Agronomy

1996~2001　Ph.D., College of Biological Sciences, China Agricultural University, Beijing, P.R. China
    Major: Plant Sciences

Employment
2001-2006, Post-doc fellow, Department of Biological Sciences, Purdue University

2006-2016, Principal Investigator, Institute of Botany, Chinese Academy of Sciences

2014-present, Principal Investigator, School of Life Sciences, Tsinghua University.

 

Research interest

    

    We are interested in dissecting the cellular mechanisms underlying plant growth and development as well as the interaction of plant with its surrounding environment. Specifically, we are focusing on two following topics:

    1) Structure, function and regulation of the plant cytoskeleton;

    2) Assembly, function and regulation of non-membranous organelles.

Selected publications

1. Li X, Zhuang Y, Zhao W, Qu X, Wang J, Chang M, Shen J, Chen N, and Huang S*. Molecular and functional adaption of Arabidopsis villins. New Phytologist, 2025;245(3):1158-1179

2. Xu Y, Shen J, Ruan H, Qu X, Li Y, Wang Y, Li P, Yi R, Ren H, Zhang Y, Huang S*. A RhoGAP controls apical actin polymerization by inhibiting formin in Arabidopsis pollen tubes. Current Biology, 2024, 34(21):5040-5053

3. Zhuang Y, Wang Y, Jiao C, Shang Z, and Huang S*. Arabidopsis VILLIN5 bundles actin filaments using a novel mechanism. Plant Journal, 2024, 119(6):2854-2866.

4. Wang J, Shen J, Xu Y, Jiang Y, Qu X, Zhao W, and Huang S*. Differential sensitivity of ADF isovariants to a pH gradient promotes pollen tube growth. Journal of Cell Biology, 2023, 222 (11): e202206074

5. Wang Q, Xu Y, Zhao S, Jiang Y, Yi R, Guo Y and Huang S*.  Activation of actin-depolymerizing factor by CDPK16-mediated phosphorylation promotes actin turnover in Arabidopsis pollen tubes. PLoS Biology, 2023;21(4):e3002073

6. Zhang R*, Xu Y, Ran Yi, Shen J and Huang S*. Actin Cytoskeleton in the Control of Vesicle Transport, Cytoplasmic Organization and Pollen Tube Tip Growth. Plant Physiology, 2023, kiad203. doi: 10.1093/plphys/kiad203

7. Jiang Y, Lu Q, and Huang S*. Functional non-equivalence of pollen ADF isovariants in Arabidopsis. Plant Journal, 2022;110(4):1068-1081

8. Zhang Y, Li Z, Chen N, Huang Y and Huang S*. Phase Separation of Arabidopsis EMB1579 Controls Transcription, mRNA Splicing and Development. PLoS Biology, 2020, 21;18(7):e3000782

9. Zhao W, Qu X, Zhuang Y, Wang L, Bosch M, Franklin-Tong VE, Xue Y, Huang S*. Villin Controls the Formation and Enlargement of Punctate Actin Foci in Pollen Tubes. Journal of Cell Science, 2020,133 (6). pii: jcs237404

10. Diao M, Li X and Huang S*. Arabidopsis AIP1 Regulates the Organization of Apical Actin Filaments via Promoting their Turnover in Pollen Tubes. Sci China Life Sci., 2020, 63(2), 239-250

11. Jiang Y, Chang M, Lan Y and Huang S*. Mechanism of CAP1-mediated Apical Actin Polymerization in Pollen Tubes. Proc Natl Acad Sci U S A., 2019;116(24):12084-12093

12. Lan Y, Liu X, Fu Y* and Huang S*. Arabidopsis Class I Formins Control Membrane-Originated Actin Polymerization at Pollen Tube Tips. PLoS Genetics, 2018, 14(11): e1007789

13. Diao M, Ren S, Wang Q, Qian L, Shen J, Liu Y and Huang S*. Arabidopsis Formin 2 Regulates Cell-to-Cell Trafficking by Capping and Stabilizing Actin Filaments at Plasmodesmata. eLife, 2018;7:e36316

14. Jiang Y, Wang J, Xie Y, Chen N and Huang S*. Arabidopsis ADF10 Shapes the Organization of Apical Actin Filaments via Promoting their Turnover and Ordering in Pollen Tubes. Journal of Cell Science, 2017, 130, 3988-4001

15. Qu X, Zhang R, Zhang M, Diao M, Xue Y and Huang S*. Organizational Innovation of Apical Actin Filaments Drives Rapid Pollen Tube Growth and Turning. Molecular Plant, 2017, 10, 930–947

Contact information

Tel: +86-10-62781946
E-mail: sjhuang@tsinghua.edu.cn