Guoqiang CHEN     Ph.D.


1981-1985  BSc, South China University of Technology, Guangzhou, China

1986-1989  PhD, Graz University of Technology, Graz, Austria

1990-1992   Postdoc., University of Nottingham, UK

1992-1994   Postdoc., University of Alberta, Canada

1994-1997   Associate Professor, Tsinghua University

1997-Present  Professor, Tsinghua University



Research interest

Synthetic Biology; Microbial Metabolic Engineering; Biological Materials; Industrial Biotechnology



Selected publications

1.         Zhao Han, Zhang Haoqian M, Li Teng, Lou Chunbo, Ouyang Qi and Chen GQ. Novel T7-Like Expression Systems Used for Halomonas. Metabolic Engineering 39 (2017) 128-140 
2.         Elhadi Dina, Lv Li, Jiang Xiaoran, Wu Hong and Chen GQ. CRISPRi Engineering E. coli for Morphology Diversification. Metabolic Engineering 38 (2016) 358-369 
3.         Jiang Xiaoran and Chen GQ. Morphology Engineering of Bacteria for Bio-production Biotechnology Advances 34 (2016) 435–440
4.         Chen GQ and Hajnal Ivan. The “PHAome”. Trends in Biotechnology 33 (2015) 559-564
5.         Jiang Xiaoran, Wang Huan, Shen Rui and Chen GQ.  Engineering the Bacterial Shapes for Enhanced Inclusion Bodies Accumulation. Metabolic Engineering 29 (2015) 227-237 
6.         Lv Li, Ren Yilin, Chen Jin Chun, Wu Qiong and Chen GQ. Application of CRISPRi for Prokaryotic Metabolic Engineering Involving Multiple Genes, A Case Study: Controllable P(3HB-co-4HB) Biosynthesis. Metabolic Engineering 29 (2015) 160–168 
7.         Yin Jin, Chen Jinchun, Wu Qiong and Chen GQ. Halomonas spp, a Rising Star for Industrial Biotechnology. Biotechnology Advance 33 (2015) 1433-1442 
8.         Tan Dan, Wu Qiong, Chen, Jin-Chun and Chen GQ. Engineering Halomonas TD01 for Low Cost Production of Polyhydroxyalkanoates. Metabolic Engineering 26 (2014) 34–47
9.         Wang Ying, Wu Hong, Jiang Xiaoran and Chen GQ. Engineering Escherichia coli for Enhanced Production of Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Larger Cellular Space. Metabolic Engineering 25 (2014) 183-193
10.         Wang Y, Yin Jin and Chen GQ. Microbial Polyhydroxyalkanoates, Challenges and Opportunities. Current Opinion in Biotechnology 30 (2014) 59-65 
11. Yue Tan, Junyi Wang, Shan Su, Qian Wang , Shibo Jiang*, Lu Lu* and          Chen YH*. Enhancement of endocytic uptake of HIV-1 virions into CD4-negative epithelial cells by HIV-1 gp41 via its interaction with POB1.          Cellular & Molecular Immunology.(2017) 14(6):568-571
12.Tan Y, Tong P, Zhao L, Li J, Wang J*,          Chen YH*. The membrane proximal region of CCR5 participates in the cellular entry of HIv-1.          Front Immunology (2017), 8:478


Contact information

Tel:010-62783844(office)     010-62772676(lab)