Jianbin Wang     Ph.D.

Associate Professor


2008  Chemistry, Peking University/B.S.

2014  Bioengineering, Stanford University/Ph.D.

2014-2015 Bioengineering, Stanford University/Postdoctoral Scholar

2015-2015 Agenovir Corporation/Consulting Scientist

2015-2021 School of Life Sciences, Tsinghua University/Assistant Professor

2021-present School of Life Sciences, Tsinghua University/Associate Professor

 

 

Research interest


Our technology-oriented lab is devoted to the development of novel strategies for accurate and quantitative molecular pathology measurements. We would like to bring the precision measurement tradition from analytical chemistry to molecular and cellular physiology, hoping to make discoveries that were previously unreachable. So far we have applied new methods on studying viral evolution, tumorigenesis, and immune responses, which were recognized by the Chinese Preventive Medicine Association Science and Technology Award and the IADR/AADOCR William J Gies Award.


Selected publications


1. F Lan#, J Li#, W Miao#, F Sun#, S Duan, Y Song, J Yao, X Wang, C Wang, X Liu*, J Wang*, L Zhang*, H Qi*. GZMK-expressing CD8+ T cells promote recurrent airway inflammatory diseases. Nature 638, 490 (2025).

2. X Shao#, M Tian#, J Yin, H Duan, Y Tian, H Wang, C Xia, Z Wang, Y Zhu, Y Wang, L Chaihu, M Tan, H Wang, Y Huang, J Wang*, G Wang*. (2024). Biofunctionalized dissolvable hydrogel microbeads enable efficient characterization of native protein complexes. Nature Communications 15, 8633 (2024).

3. Y Lin#, Z Wan#, B Liu#, J Yao#, T Li, F Yang, J Sui, Y Zhao, W Liu, X Zhou, J Wang*, H Qi*. (2024). B cell-reactive triad of B cells, follicular helper and regulatory T cells at homeostasis. Cell Research.

4. T Chang#, W Han#, M Jiang#, J Li#, Z Liao, M Tang, J Zhang, J Shen, Z Chen, P Fei, X Ren, Y Pang, G Wang, J Wang*, Y Huang*. (2023). Rapid and signal crowdedness-robust in situ sequencing through hybrid block coding. PNAS 120, e2309227120.

5. X Liu#, J Yao#, Y Zhao, J Wang*, Hai Qi*. (2022). Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota. Nature Immunology 23, 1564.

6. R Li#, L Di#, J Li#, W Fan#, Y Liu, W Guo, W Liu, L Liu, Q Li, L Chen, Y Chen, C Miao, H Liu, Y Wang, Y Ma, D Xu, D Lin*, Y Huang*, J Wang*, F Bai*, Chen Wu*. (2021). A body map of somatic mutagenesis in morphologically normal human tissues. Nature 597, 398.

7. C Chen#, J Li#, L Di#, Q Jing#, P Du#, C Song, J Li, Q Li, Y Cao, XS Xie, AR Wu*, H Zeng*, Y Huang*, and J Wang*. (2020). MINERVA: A Facile Strategy for SARS-CoV-2 Whole-Genome Deep Sequencing of Clinical Samples. Molecular Cell 80, 1123.

8. L Di#, Y Fu#, Y Sun, J Li, L Liu, J Yao, G Wang, Y Wu, K Lao, RW Lee, G Zheng, J Xu, J Oh, D Wang, XS Xie*, Y Huang*, and J Wang*. (2020). RNA sequencing by direct tagmentation of RNA/DNA hybrids. PNAS 117, 2886.

 

Contact information


Tel:+86-10-62789280

E-mail:jianbinwang[at]tsinghua.edu.cn

Website:http://accuquantbio.life.tsinghua.edu.cn

Address:清华大学医学科学楼C238