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Jinchun CHEN, M.S.

Associate Professor

Education Experiences:

1987-1992, B.S., Tsinghua University

1992-1995, M.S., Tsinghua University

Job Experiences:

1995-1997, Tutor in the DBSB, Tsinghua University

1996-1997, Research Assistant in ABCT, HongKong Polytechnic U

1997-2005, Lecturer in the DBSB, Tsinghua University

2005-present, Associate Professor for School of Life Sciences, Tsinghua University

Research interest

Industrial Microbiology and Biological Chemical Engineering. Focus on biotransformation of chemical intermediate, synthesis and application of new biomaterial and special macromolecular material.

Selected publications

1）Wang Huan, Ye Jian-Wen, Chen Xinyu, Yuan Yiping Shi Jingwen, Liu Xinyi, Yang Fang , Ma Yueyuan, Chen Jinchun, Wu Fuqing, Lan Yuxuan, Wu Qiong, Tong Yi, Chen Guo-Qiang. Production of PHA copolymers consisting of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx) by recombinant Halomonas bluephagenesis. Chemical Engineering Journal 466 (2023) 143261

2）Zheng Yang, Chen Jin-Chun, Ma Yi-Ming, Chen Guo-Qiang. Engineering biosynthesis of polyhydroxyalkanoates (PHA) for diversity and cost reduction. Metabolic engineering. 58 (2020) 82-93

3）Du Hetong, Zhao Yiqing, Wu Fuqing, Chen Jinchun, Jiang Xiaoran, Ye Jianwen, Chen Guo-Qiang. Engineering Halomonas bluephagenesis for L-Threonine Production. Metabolic Engineering 60 (2020) 119–127

4) Chen Guo-Qiang, Chen Xin-Yu, Wu Fu-Qing and Chen Jinchun. Polyhydroxyalkanoates (PHA) Toward Cost Competitiveness and Functionality. Advanced Industrial Engineering Polymer Research 3 (2020) 1-7

5）Ah-Leum Chung#, Guo-Dong Zeng#, Hong-Liang Jin, Qiong Wu, Jin-Chun Chen*, Guo-Qiang Chen*. Production of medium-chain-length 3-hydroxyalkanoic acids by beta-oxidation and phaC operon deleted Pseudomonas entomophila harboring thioesterase gene. Metabolic Engineering 2013,17 :23–29.

6）Xiao-Yun Zhou#, Xiao-Xi Yuan#, Zhen-Yu Shi, De-Chuang Meng, Wen-Jun Jiang, Lin-Ping Wu, Jin-Chun Chen* and Guo-Qiang Chen*. Hyperproduction of poly(4-hydroxybutyrate) from glucose by recombinant Escherichia coli. Microbial Cell Factories. 2012, 11:54-61

7）Zhou XY, Yuan XX, Shi ZY, Meng DC, Jiang WJ, Wu LP, Chen JC* and Chen GQ*.（2012）Hyperproduction of poly(4-hydroxybutyrate) from glucose by recombinant Escherichia coli. Microbial Cell Factories. 11:54-61.

8）Hu D, Zheng M, Zhang X, Wu Q, Chen JC* and Chen GQ*. Biosynthesis and Characterization of Polyhydroxyalkanoate Block Copolymer P3HB-b-P4HB. Biomacromolecules. 2011，12： 3166-3173

9）Zhou Q, Shi ZY, Meng DC, Wu Q, Chen JC* and Chen GQ*. Production of 3-Hydroxypropionate Homopolymer and Poly(3-Hydroxypropionate-co- 4-hydroxybutyrate) Copolymer by Recombinant Escherichia coli. Metabolic Engineering. 2011，13：777–785

10）Sun SY, Zhang X, Zhou Q, Chen Jin-Chun*, Chen GQ*. Microbial production of cis-1,2-dihydroxy-cyclohexa-3,5-diene-1-carboxylate by genetically modified Pseudomonas putida. Appl Microbiol Biotechnol. 2008, 80:977-984

11）Ouyang SP, Liu Q, Sun SY, Chen Jin-Chun, Chen GQ. Genetic engineering of Pseudomonas putida KT2442 for biotransformation of aromatic compounds to chiral cis-diols. Journal of Biotechnology 2007, 132: 246–250

12）Wang YW, Wu Q, Chen Jin-Chun, Chen GQ Evaluation of three-dimensional scaffolds made of blends of hydroxyapatite and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for bone reconstruction. Biomaterials. 2005. 26(8): 899-904.

13）Zheng Z; Gong Q; Liu T; Deng Y; Chen Jin-Chun; Chen GQ. Thioesterase II of Escherichia coli plays an important role in 3-hydroxydecanoic acid production. Applied and Environmental Microbiology. 2004, 70 (7): 3807-3813.

14）Chen JY; Liu T; Zheng Z; Chen Jin-Chun, Chen GQ. Polyhydroxyalkanoate synthases PhaC1 and PhaC2 from Pseudomonas stutzeri 1317 had different substrate specificities. FEMS Microbiology Letters. 2004. 234(2): 231-237.

Textbooks:

Bioreaction Engineering Principles(2011)

Experimental Instruction for College Life Science(2022)

Experimental Instruction for Fundamental Life Science (2009)

Experimental Instruction for Microbiology (2005, 2007,2023)

Experimental Instruction for Modern Biology(1999)

Awards

2nd Class, Production and Development of Bioplastics（PHBHHx）National Technology Invention Award, China (2002)

1st Class, Production and Applied Research on Bioplastics（PHBHHx）, Progress Award of Science and Technology, Beijing, China(2001)

Silver Prize，Bioplastics，the 2003 Nuremberg new ideas, new inventions, new products exhibition, Germany

2nd Class, Basic Applied Research on Microbial Polyhydroxyalkanoate (PHA), Progress Award of Science and Technology, Beijing, China (2012)

2nd Class, Outstanding class adviser, Tsinghua University （2014）

2nd Class, Teaching Deed for Microbiology Experiments, Tsinghua University (1996)

Contact information

Lab of Microbiology, School of Life Sciences, Tsinghua University, Beijing 100084, China

Tel (Fax): +86-10-62788784