谢道昕 博士
教授 中国科学院院士
2006-现在:清华大学(教授)
2002-2006:新加坡分子细胞生物所(实验室主任,资深科学家)
1999-2002:新加坡国立大学农业分子生物所(实验室主任,助理教授)
1994-1999:英国East Anglia大学(Senior Research Associate)
1990-1994:英国John Innes研究中心和英国Leicester大学(Research Associate)
1984-1990:中国农科院研究生院(Ph.D.和MSc)
1983-1984:湖南棉花科学研究所(Research Assistant)
1979-1983:湖南农学院(BSc.)
● 研究兴趣、领域:
激素对于生物的生长发育、新陈代谢和繁衍生息等各种生命活动起重要调节作用;阐明激素的受体感知机制及信号传导机制,对于揭示生命现象的本质、提高生物的生存和发展能力具有重要意义。谢道昕实验室主要从事植物激素的研究工作,研究植物激素调控植物生长发育和防御反应的分子机制,研究茉莉素和独脚金内酯的受体感知机制。
● 开设的课程:
《植物科学导论》,《植物分子遗传研讨课》、《科技写作基本要素》
● 代表性论文:
1.Wang J, Wu D, Pei G, Wang Y, Liu X, Tian S, Zhang Z, Zhang X, Li P, Xie D, Shan X. The pathogen effector BcSSP2 suppresses the NPC phase separation to facilitate Botrytis cinerea infection. Nature Communications, 2025, 16(1):8610.
2.Li R, Yang Y, Lou H, Wang W, Du R, Chen H, Du X, Hu S, Wang G, Yan J, Shan X, Xie D. Glutathione triggers leaf-to-leaf, calcium-based plant defense signaling. Nature Communications, 2025, 16(1): 1915.
3.Wang J, Pei G, Wang Yu, Wu D, Liu X, Li G, He J, Zhang X, Shan X, Li P, Xie D. Phase separation of the nuclear pore complex facilitates selective nuclear transport to regulate plant defense against pathogen and pest invasion. Molecular Plant, 2023, 16(6): 1016-1030.
4.Hu S, Yu K, Yan J, Shan X, Xie D. Jasmonate perception: Ligand-receptor interaction, regulation, and evolution. Molecular Plant, 2023, 16(1): 23-42.
5.Yao R, Chen L, Xie D. Irreversible strigolactone recognition: a non-canonical mechanism for hormone perception. Current Opinion in Plant Biology, 2018, 45(Pt A): 155-161.
6.Yan J, Yao R, Chen L, Li S, Gu M, Nan F, Xie D. Dynamic perception of jasmonates by the F-Box protein COI1. Molecular Plant, 2018, 11(10): 1237-1247.
7.Yan C, Fan M, Yang M, Zhao J, Zhang W, Su Y, Xiao L, Deng H, Xie D. Injury activates Ca2+/calmodulin-dependent phosphorylation of JAV1-JAZ8-WRKY51 complex for jasmonate biosynthesis. Molecular Cell, 2018, 70(1): 136-149.
8.Wu D, Qi T, Li W, Tian H, Gao H, Wang J, Ge J, Yao R, Ren C, Wang X, Liu Y, Kang L, Ding SW, Xie D. Viral effector protein manipulates host hormone signaling to attract insect vectors. Cell Research, 2017, 27(3): 402-415.
9.Yao R, Wang F, Ming Z, Du X, Chen L, Wang, Zhang W, Deng H, Xie D. ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds. Cell Research, 2017, 27(6): 838-841.
10.Yao R, Ming Z, Yan L, Li S, Wang F, Ma S, Yu C, Yang M, Chen L, Chen L, Li Y, Yan C, Miao D, Sun Z, Yan J, Sun Y, Wang L, Chu J, Fan S, He W, Deng H, Nan F, Li J, Rao Z, Lou Z, Xie D. DWARF14 is a non-canonical hormone receptor for strigolactone. Nature, 2016, 536(7617): 469-473.
11.Qi T, Wang J, Huang H, Liu B, Gao H, Liu Y, Song S, Xie D. Regulation of jasmonate-induced leaf senescence by antagonism between bHLH Subgroup IIIe and IIId factors in Arabidopsis. Plant Cell, 2015, 27(6): 1634-1649.
12.Qi T, Huang H, Song S, Xie D. Regulation of jasmonate-mediated stamen development and seed production by a bHLH-MYB complex in Arabidopsis.Plant Cell, 2015, 27(6): 1620-1633.
13.Qi T, Huang H, Wu D Yan J, Qi Y, Song S, Xie D. Arabidopsis DELLA and JAZ proteins bind the WD-repeat/bHLH/MYB complex to modulate gibberellin and jasmonate signaling synergy. Plant Cell, 2014, 26(3): 1118-1133.
14.Song S, Huang H, Gao H, Wang J, Wu D, Liu X, Yang S, Zhai Q, Li C, Qi T, Xie D. Interaction between MYC2 and ETHYLENE INSENSITIVE3 modulates antagonism between jasmonate and ethylene signaling in Arabidopsis. Plant Cell, 2014, 26(1): 263-279.
15.Hu P, Zhou W, Cheng Z, Fan M, Wang L, Xie D. JAV1 controls jasmonate-regulated plant defense. Molecular Cell, 2013, 50(4): 504-515.
● 联系方式:
Tel:+86-10-62781575 (office); 62773664 (lab)
Fax:+86-10-62798201
E-mail: daoxinlab(at)tsinghua(dot)edu(dot)cn