科研成果

  • 2-Hydroxyisobutyrylation on histone H4K8 is regulated by glucose homeostasis in Saccharomyces cerevisiae

    Huang, Jing; Luo, Zhouqing; Ying, Wantao; Cao, Qichen; Huang, He; Dong, Junkai; Wu, Qingyu; Zhao, Yingming; Qian, Xiaohong; Dai, Junbiao

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  • A C-terminally truncated form of beta-catenin acts as a novel regulator of Wnt/beta-catenin signaling in planarians

    Su, Hanxia; Sureda-Gomez, Miquel; Rabaneda-Lombarte, Neus; Gelabert, Maria; Xie, Jianlei; Wu, Wei; Adell, Teresa

    PLOS GENETICS

  • A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response

    Wu, Xiu-Yun; Li, Tian

    FRONTIERS IN PLANT SCIENCE

  • A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters

    Yan, Nieng

    JOURNAL OF MOLECULAR BIOLOGY

  • A Novel Matrix Protein, PfY2, Functions as a Crucial Macromolecule during Shell Formation

    Yan, Yi; Yang, Dong; Yang, Xue; Liu, Chuang; Xie, Jun; Zheng, Guilan; Xie, Liping; Zhang, Rongqing

    SCIENTIFIC REPORTS

  • A deep learning framework for improving long-range residue-residue contact prediction using a hierarchical strategy

    Xiong, Dapeng; Zeng, Jianyang; Gong, Haipeng

    BIOINFORMATICS

  • A mitochondria-targeting artemisinin derivative with sharply increased antitumor but depressed anti-yeast and anti-malaria activities

    Sun, Chen; Cao, Yu; Zhu, Pan; Zhou, Bing

    SCIENTIFIC REPORTS

  • A potent human neutralizing antibody Fc-dependently reduces established HBV infections

    Li, Dan; He, Wenhui; Liu, Ximing; Zheng, Sanduo; Qi, Yonghe; Li, Huiyu; Mao, Fengfeng; Liu, Juan; Sun, Yinyan; Pan, Lijing; Du, Kaixin; Ye, Keqiong; Li, Wenhui; Sui, Jianhua

    ELIFE

  • A receptor-like protein acts as a specificity switch for the regulation of stomatal development

    Lin, Guangzhong; Zhang, Liang; Han, Zhifu; Yang, Xinru; Liu, Weijia; Li, Ertong; Chang, Junbiao; Qi, Yijun; Shpak, Elena D.; Chai, Jijie

    GENES & DEVELOPMENT

  • ADF10 shapes the overall organization of apical actin filaments by promoting their turnover and ordering in pollen tubes

    Jiang, Yuxiang; Wang, Juan; Xie, Yurong; Chen, Naizhi; Huang, Shanjin

    JOURNAL OF CELL SCIENCE

  • Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells

    Wang, Lu; Xu, Xuanhao; Cao, Yaqiang; Li, Zhongwei; Cheng, Hao; Zhu, Gaoyang; Duan, Fuyu; Na, Jie; Han, Jing-Dong J.; Chen, Ye-Guang

    JOURNAL OF BIOLOGICAL CHEMISTRY

  • Activity-induced histone modifications govern Neurexin-1 mRNA splicing and memory preservation

    Ding, Xinlu; Liu, Sanxiong; Tian, Miaomiao; Zhang, Wenhao; Zhu, Tao; Li, Dongdong; Wu, Jiawei; Deng, HaiTeng; Jia, Yichang; Xie, Wei; Xie, Hong; Guan, Ji-Song

    NATURE NEUROSCIENCE

  • Adipose angiotensin II type 1 receptor-associated protein ameliorates metabolic disorders via promoting adipose tissue adipogenesis and browning

    Luo, Chengting; Lv, Na; Chang, Zai; Qu, Qiannuo; Huang, Jianzhen

    EUROPEAN JOURNAL OF CELL BIOLOGY

  • Aldehyde dehydrogenase 1A1 increases NADH levels and promotes tumor growth via glutathione/dihydrolipoic acid-dependent NAD(+) reduction

    Wang, Baiyun; Chen, Xue; Wang, Zixi; Xiong, Wei; Xu, Tao; Zhao, Xinyuan; Cao, Yang; Guo, Yanru; Li, Lin; Chen, She; Huang, Song; Wang, Xiaodong; Fang, Min; Shen, Zhirong

    ONCOTARGET

  • Allelic reprogramming of 3D chromatin architecture during early mammalian development

    Du, Zhenhai; Zheng, Hui; Huang, Bo; Ma, Rui; Wu, Jingyi; Zhang, Xianglin; He, Jing; Xiang, Yunlong; Wang, Qiujun; Li, Yuanyuan; Ma, Jing; Zhang, Xu; Zhang, Ke; Wang, Yang; Zhang, Michael Q.; Gao, Juntao; Dixon, Jesse R.; Wang, Xiaowo; Zeng, Jianyang; Xie, Wei

    NATURE

  • An Accurate Prediction of Protein Melting Temperature Directly from Amino Acid Sequence

    Leng, Fei; Pan, Xian-Ming

    NANOSCIENCE AND NANOTECHNOLOGY LETTERS

  • An Arabidopsis ABC Transporter Mediates Phosphate Deficiency-Induced Remodeling of Root Architecture by Modulating Iron Homeostasis in Roots

    Dong, Jinsong; Pineros, Miguel A.; Li, Xiaoxuan; Yang, Haibing; Liu, Yu; Murphy, Angus S.; Kochian, Leon V.; Liu, Dong

    MOLECULAR PLANT

  • An Atomic Structure of the Human Spliceosome

    Zhang, Xiaofeng; Yan, Chuangye; Hang, Jing; Finci, Lorenzo I.; Lei, Jianlin; Shi, Yigong

    CELL

  • Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of A beta 42 and A beta 40 peptides by gamma-secretase

    Sun, Linfeng; Zhou, Rui; Yang, Guanghui; Shi, Yigong

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  • Antiviral Resistance Protein Tm-2(2) Functions on the Plasma Membrane

    Chen, Tianyuan; Liu, Dan; Niu, Xiaolin; Wang, Junzhu; Qian, Lichao; Han, Lu; Liu, Na; Zhao, Jinping; Hong, Yiguo; Liu, Yule

    PLANT PHYSIOLOGY

  • Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia

    Liu, Yao-Nan; Lu, Si-Yao; Yao, Jun

    PSYCHIATRY AND CLINICAL NEUROSCIENCES

  • Arabidopsis ABI5 plays a role in regulating ROS homeostasis by activating CATALASE 1 transcription in seed germination

    Bi, Chao; Ma, Yu; Wu, Zhen; Yu, Yong-Tao; Liang, Shan; Lu, Kai; Wang, Xiao-Fang

    PLANT MOLECULAR BIOLOGY

  • Arabidopsis ALA1 and ALA2 Mediate RNAi-Based Antiviral Immunity

    Zhu, Biyun; Gao, Hua; Xu, Gang; Wu, Dewei; Song, Susheng; Jiang, Hongshan; Zhu, Shuifang; Qi, Tiancong; Xie, Daoxin

    FRONTIERS IN PLANT SCIENCE

  • Arabidopsis MYB24 Regulates Jasmonate-Mediated Stamen Development

    Huang, Huang; Gao, Hua; Liu, Bei; Qi, Tiancong; Tong, Jianhua; Xiao, Langtao; Xie, Daoxin; Song, Susheng

    FRONTIERS IN PLANT SCIENCE

  • Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2

    Guo, Runyu; Zong, Shuai; Wu, Meng; Gu, Jinke; Yang, Maojun

    CELL

  • Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation

    Zheng, Jing-Xiang; Li, Yan; Ding, Yue-He; Liu, Jun-Jie; Zhang, Mei-Jun; Dong, Meng-Qiu; Wang, Hong-Wei; Yu, Li

    AUTOPHAGY

  • Atomic modeling of the ITS2 ribosome assembly subcomplex from cryo-EM together with mass spectrometry-identified protein-protein crosslinks

    Wu, Shan; Tan, Dan; Woolford, John L., Jr.; Dong, Meng-Qiu; Gao, Ning

    PROTEIN SCIENCE

  • Autophagy functions as an antiviral mechanism against geminiviruses in plants

    Haxim, Yakupjan; Ismayil, Asigul; Jia, Qi; Wang, Yan; Zheng, Xiyin; Chen, Tianyuan; Qian, Lichao; Liu, Na; Wang, Yunjing; Han, Shaojie; Cheng, Jiaxuan; Qi, Yijun; Hong, Yiguo; Liu, Yule

    ELIFE

  • BMP restricts stemness of intestinal Lgr5(+) stem cells by directly suppressing their signature genes

    Qi, Zhen; Li, Yehua; Zhao, Bing; Xu, Chi; Liu, Yuan; Li, Haonan; Zhang, Bingjie; Wang, Xinquan; Yang, Xiao; Xie, Wei; Li, Baojie; Han, Jing-Dong Jackie; Chen, Ye-Guang

    NATURE COMMUNICATIONS

  • Basement Membrane Manipulation in Drosophila Wing Discs Affects Dpp Retention but Not Growth Mechanoregulation

    Ma, Mengqi; Cao, Xueya; Dai, Jianli; Pastor-Pareja, Jose C.

    DEVELOPMENTAL CELL

  • Biological cryo-electron microscopy in China

    Wang, Hong-Wei; Lei, Jianlin; Shi, Yigong

    PROTEIN SCIENCE

  • CED-10-WASP-Arp2/3 signaling axis regulates apoptotic cell corpse engulfment in C. elegans

    Wu, Dou; Chai, Yongping; Zhu, Zhiwen; Li, Wenjing; Ou, Guangshuo; Li, Wei

    DEVELOPMENTAL BIOLOGY

  • COME: a robust coding potential calculation tool for lncRNA identification and characterization based on multiple features

    Hu, Long; Xu, Zhiyu; Hu, Boqin; Lu, Zhi John

    NUCLEIC ACIDS RESEARCH

  • Capture and Release of tRNA by the T-Loop Receptor in the Function of the T-Box Riboswitch

    Fang, Xianyang; Michnicka, Malgorzata; Zhang, Yikan; Wang, Yun-Xing; Nikonowicz, Edward P.

    BIOCHEMISTRY

  • Catalytic and Enantioselective Diels-Alder Reactions of (E)-4-Oxopent-2-enoates

    Zhang, Su-Lei; Lu, Yong; Li, Yuan-He; Wang, Kuang-Yu; Chen, Jia-Hua; Yang, Zhen

    ORGANIC LETTERS

  • Centriole translocation and degeneration during ciliogenesis in Caenorhabditis elegans neurons

    Li, Wenjing; Yi, Peishan; Zhu, Zhiwen; Zhang, Xianliang; Li, Wei; Ou, Guangshuo

    EMBO JOURNAL

  • Co-production of microbial polyhydroxyalkanoates with other chemicals

    Li, Tian; Elhadi, Dina; Chen, Guo-Qiang

    METABOLIC ENGINEERING

  • Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population

    Yu, H. G; Yan, H. K; Li, J. M; Li, Z. P; Zhang, X. D; Ma, Y. C; Mei, L. R; Liu, C. K; Cai, L. T; Wang, Q. V; Zhang, F. S; Iwata, N. D; Ikeda, M. E; Wang, L. P; Lu, T. M; Li, M. K; Xu, H. R; Wu, X. D; Liu, B. C; Yang, J. I; Li, K. R; Lv, L. N; Ma, X. A; Wang, C. T; Li, L. P; Yang, F. K; Jiang, T. L; Shi, Y. R; Li, T. P; Zhang, D. C; Yue, W. T; Chinese Schizophrenia Collaboratio

    MOLECULAR PSYCHIATRY

  • Comparative Proteomics Reveals Timely Transport into Cilia of Regulators or Effectors as a Mechanism Underlying Ciliary Disassembly

    Wang, Limei; Gu, Lixiao; Meng, Dan; Wu, Qiong; Deng, Haiteng; Pan, Junmin

    JOURNAL OF PROTEOME RESEARCH

  • Comprehensive Proteomics Analysis Reveals Metabolic Reprogramming of Tumor-Associated Macrophages Stimulated by the Tumor Microenvironment

    Liu, Di; Chang, Cheng; Lu, Ning; Wang, Xing; Lu, Qian; Ren, Xiaojie; Ren, Peng; Zhao, Dianyuan; Wang, Lijing; Zhu, Yunping; He, Fuchu; Tang, Li

    JOURNAL OF PROTEOME RESEARCH

  • Comprehensive assessment showed no associations of variants at the SLC10A1 locus with susceptibility to persistent HBV infection among Southern Chinese

    Zhang, Ying; Li, Yuanfeng; Wu, Miantao; Cao, Pengbo; Liu, Xiaomin; Ren, Qian; Zhai, Yun; Xie, Bobo; Hu, Yanling; Hu, Zhibin; Bei, Jinxin; Ping, Jie; Liu, Xinyi; Yu, Yinghua; Guo, Bingqian; Lu, Hui; Liu, Guanjun; Zhang, Haitao; Cui, Ying; Mo, Zengnan; Shen, Hongbing; Zeng, Yi-Xin; He, Fuchu; Zhang, Hongxing; Zhou, Gangqiao

    SCIENTIFIC REPORTS

  • Conserved gene regulatory module specifies lateral neural borders across bilaterians

    Li, Yongbin; Zhao, Di; Horie, Takeo; Chen, Geng; Bao, Hongcun; Chen, Siyu; Liu, Weihong; Horie, Ryoko; Liang, Tao; Dong, Biyu; Feng, Qianqian; Tao, Qinghua; Liu, Xiao

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  • Construction of Comprehensive Dosage-Matching Core Histone Mutant Libraries for Saccharomyces cerevisiae

    Jiang, Shuangying; Liu, Yan; Wang, Ann; Qin, Yiran; Luo, Maoguo; Wu, Qingyu; Boeke, Jef D.; Dai, Junbiao

    GENETICS

  • Construction, characterization and application of a genome-wide promoter library in Saccharomyces cerevisiae

    Yuan, Ting; Guo, Yakun; Dong, Junkai; Li, Tianyi; Zhou, Tong; Sun, Kaiwen; Zhang, Mei; Wu, Qingyu; Xie, Zhen; Cai, Yizhi; Cao, Limin; Dai, Junbiao

    FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING

  • Control of lipid droplet fusion and growth by CIDE family proteins

    Gao, Guangang; Chen, Feng-Jung; Zhou, Linkang; Su, Lu; Xu, Dijin; Xu, Li; Li, Peng

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

  • Controlling cell volume for efficient PHB production by Halomonas

    Jiang, Xiao-Ran; Yao, Zhi-Hao; Chen, Guo-Qiang

    METABOLIC ENGINEERING

  • Controlling microbial PHB synthesis via CRISPRi

    Li, Dan; Lv, Li; Chen, Jin-Chun; Chen, Guo-Qiang

    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

  • Coupling between ATP hydrolysis and protein conformational change in maltose transporter

    Lv, Xiaoying; Liu, Hao; Chen, Haifeng; Gong, Haipeng

    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

  • Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and-C2

    Ma, Meisheng; Liu, Jun-Jie; Li, Yan; Huang, Yuwei; Ta, Na; Chen, Yang; Fu, Hua; Ye, Ming-Da; Ding, Yuehe; Huang, Weijiao; Wang, Jia; Dong, Meng-Qiu; Yu, Li; Wang, Hong-Wei

    CELL RESEARCH

  • Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange

    Xu, Jingfei; Zhao, Lingyun; Xu, Yuanyuan; Zhao, Weixing; Sung, Patrick; Wang, Hong-Wei

    NATURE STRUCTURAL & MOLECULAR BIOLOGY

  • Cryo-EM structures of human gamma-secretase

    Yang, Guanghui; Zhou, Rui; Shi, Yigong

    CURRENT OPINION IN STRUCTURAL BIOLOGY

  • Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii

    Li, Zhifei; Guo, Qiang; Zheng, Lvqin; Ji, Yongsheng; Xie, Yi-Ting; Lai, De-Hua; Lun, Zhao-Rong; Suo, Xun; Gao, Ning

    CELL RESEARCH

  • Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution

    Sun, Shan; Li, Lin; Yang, Fan; Wang, Xiaojing; Fan, Fenghui; Yang, Mengyi; Chen, Chunlai; Li, Xueming; Wang, Hong-Wei; Sui, Sen-Fang

    NATURE COMMUNICATIONS

  • Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states

    Zhou, Xiaoyuan; Li, Minghui; Su, Deyuan; Jia, Qi; Li, Huan; Li, Xueming; Yang, Jian

    NATURE STRUCTURAL & MOLECULAR BIOLOGY

  • Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism

    Zhang, Sensen; Li, Ningning; Zeng, Wenwen; Gao, Ning; Yang, Maojun

    PROTEIN & CELL

  • Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin

    Guan, Ruifang; Zhang, Lei; Su, Qian Peter; Mickolajczyk, Keith J.; Chen, Geng-Yuan; Hancock, William O.; Sun, Yujie; Zhao, Yongfang; Chen, Zhucheng

    NATURE COMMUNICATIONS

  • Cysteine protease cathepsin B mediates radiation-induced bystander effects

    Peng, Yu; Zhang, Man; Zheng, Lingjun; Liang, Qian; Li, Hanzeng; Chen, Jeng-Ting; Guo, Hongyan; Oshina, Sawako Y.; Chen, Yu-Zen; Zhao, Xiang; Wu, Xiaoqi; Liu, Bin; Mitani, Shohei; Yu, Jau-Song; Xue, Ding

    NATURE

  • DNA Topoisomerase 1 Prevents R-loop Accumulation to Modulate Auxin-Regulated Root Development in Rice

    Shafiq, Sarfraz; Chen, Chunli; Yang, Jing; Cheng, Lingling; Ma, Fei; Widemann, Emilie; Sun, Qianwen

    MOLECULAR PLANT

  • Determinants of Thermostability in Serine Hydroxymethyltransferase Identified by Principal Component Analysis

    Leng, Fei; Wu, Lu-Yun; Lu, Chang; Pan, Xian-Ming

    SCIENTIFIC REPORTS

  • Dimeric structure of the uracil: proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters

    Yu, Xinzhe; Yang, Guanghui; Yan, Chuangye; Baylon, Javier L.; Jiang, Jing; Fan, He; Lu, Guifeng; Hasegawa, Kazuya; Okumura, Hideo; Wang, Tingliang; Tajkhorshid, Emad; Li, Shuo; Yan, Nieng

    CELL RESEARCH

  • Direct Observation of Nacre Proteins in the Whole Calcite by Super resolution Microscopy Reveals Diverse Occlusion Patterns

    Liu, Chuang; Du, Jinzhe; Xie, Liping; Zhang, Rongqing

    CRYSTAL GROWTH & DESIGN

  • Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways

    Shao, Lisha; Lu, Binyan; Wen, Zhexing; Teng, Shaolei; Wang, Lingling; Zhao, Yi; Wang, Liyuan; Ishizuka, Koko; Xu, Xiufeng; Sawa, Akira; Song, Hongjun; Ming, Guoli; Zhong, Yi

    HUMAN MOLECULAR GENETICS

  • Dissecting Nucleosome Function with a Comprehensive Histone H2A and H2B Mutant Library

    Jiang, Shuangying; Liu, Yan; Xu, Caiyue; Wang, Yun; Gong, Jianhui; Shen, Yue; Wu, Qingyu; Boeke, Jef D.; Dai, Junbiao

    G3-GENES GENOMES GENETICS

  • Dynein-Driven Retrograde Intraflagellar Transport Is Triphasic in C. elegans Sensory Cilia

    Yi, Peishan; Li, Wen-Jun; Dong, Meng-Qiu; Ou, Guangshuo

    CURRENT BIOLOGY

  • E-M, an Engineered Endostatin with High ATPase Activity, Inhibits the Recruitment and Alternative Activation of Macrophages in Non-small Cell Lung Cancer

    Xu, Min; Zhang, Shaosen; Jia, Lin; Wang, Shan; Liu, Jie; Ma, Xuhui; Wang, Chunying; Fu, Yan; Luo, Yongzhang

    FRONTIERS IN PHARMACOLOGY

  • EMBuilder: A Template Matching-based Automatic Model-building Program for High-resolution Cryo-Electron Microscopy Maps

    Zhou, Niyun; Wang, Hongwei; Wang, Jiawei

    SCIENTIFIC REPORTS

  • Effects of Gardenia jasminoides extracts on cognition and innate immune response in an adult Drosophila model of Alzheimer's disease

    Ma Wei-Wei; Tao Ye; Wang Yan-Ying; Peng I-Feng

    CHINESE JOURNAL OF NATURAL MEDICINES

  • Effects of cataract-causing mutations W59C and W151C on beta B2-crystallin structure, stability and folding

    Zhao, Wei-Jie; Xu, Jia; Chen, Xiang-Jun; Liu, Hui-Hui; Yao, Ke; Yan, Yong-Bin

    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

  • Efficient ASK-assisted system for expression and purification of plant F-box proteins

    Li, Haiou; Yao, Ruifeng; Ma, Sui; Hu, Shuai; Li, Suhua; Wang, Yupei; Yan, Chun; Xie, Daoxin; Yan, Jianbin

    PLANT JOURNAL

  • Electrophysiological Study of Synaptotagmin I Deletion Using CRISPR/Cas9

    Yang Bo; Zheng Yi; Lu Si-Yao; Yao Jun

    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS

  • Endostatin sensitizes p53-deficient non-small-cell lung cancer to genotoxic chemotherapy by targeting DNA-dependent protein kinase catalytic subunit

    Jia, Lin; Lu, Xin-an; Liu, Guanghua; Wang, Shan; Xu, Min; Tian, Yang; Zhang, Shaosen; Fu, Yan; Luo, Yongzhang

    JOURNAL OF PATHOLOGY

  • Engineering Halomonas bluephagenesis TD01 for non-sterile production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate)

    Chen, Xiangbin; Yin, Jin; Ye, Jianwen; Zhang, Haoqian; Che, Xuemei; Ma, Yiming; Li, Mengyi; Wu, Lin-Ping; Chen, Guo-Qiang

    BIORESOURCE TECHNOLOGY

  • Engineering Halomonas species TD01 for enhanced polyhydroxyalkanoates synthesis via CRISPRi

    Tao, Wei; Lv, Li; Chen, Guo-Qiang

    MICROBIAL CELL FACTORIES

  • Engineering the ribosomal DNA in a megabase synthetic chromosome

    Zhang, Weimin; Zhao, Guanghou; Luo, Zhouqing; Lin, Yicong; Wang, Lihui; Guo, Yakun; Wang, Ann; Jiang, Shuangying; Jiang, Qingwen; Gong, Jianhui; Wang, Yun; Hou, Sha; Huang, Jing; Li, Tianyi; Qin, Yiran; Dong, Junkai; Qin, Qin; Zhang, Jiaying; Zou, Xinzhi; He, Xi; Zhao, Li; Xiao, Yibo; Xu, Meng; Cheng, Erchao; Huang, Ning; Zhou, Tong; Shen, Yue; Walker, Roy; Luo, Yisha; Kuang, Zheng; Mitchell, Leslie A.; Yang, Kun; Richardson, Sarah M.; Wu, Yi; Li, Bing-Zhi; Yuan, Ying-Jin; Yang, Huanming; Lin, Jiwei; Chen, Guo-Qiang; Wu, Qingyu; Bader, Joel S.; Cai, Yizhi; Boeke, Jef D.; Dai, Junbiao

    SCIENCE

  • Establishing knowledge on the sequence arrangement pattern of nucleated protein folding

    Leng, Fei; Xu, Chao; Xia, Xia-Yu; Pan, Xian-Ming

    PLOS ONE

  • Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions

    Yao, Pengbo; Sun, Huishan; Xu, Chang; Chen, Taiqi; Zou, Bing; Jiang, Peng; Du, Wenjing

    JOURNAL OF BIOLOGICAL CHEMISTRY

  • Expression, Purification, and Enzymatic Characterization of Intramembrane Proteases

    Zhou, R.; Shi, Y.; Yang, G.; Gelb, MH

    ENZYMOLOGY AT THE MEMBRANE INTERFACE: INTRAMEMBRANE PROTEASES

  • Fasting-induced hormonal regulation of lysosomal function

    Chen, Liqun; Wang, Ke; Long, Aijun; Jia, Liangjie; Zhang, Yuanyuan; Deng, Haiteng; Li, Yu; Han, Jinbo; Wang, Yiguo

    CELL RESEARCH

  • Formation of a Snf1-Mec1-Atg1 Module on Mitochondria Governs Energy Deprivation-Induced Autophagy by Regulating Mitochondrial Respiration

    Yi, Cong; Tong, Jingjing; Lu, Puzhong; Wang, Yizheng; Zhang, Jinxie; Sun, Chen; Yuan, Kangning; Xue, Renyu; Zou, Bing; Li, Nianzhong; Xiao, Shuhua; Dai, Chong; Huang, Yuwei; Xu, Liling; Li, Lin; Chen, She; Miao, Di; Deng, Haiteng; Li, Hongliang; Yu, Li

    DEVELOPMENTAL CELL

  • Functional Disruption of a Chloroplast Pseudouridine Synthase Desensitizes Arabidopsis Plants to Phosphate Starvation

    Lu, Shan; Li, Chenyi; Zhang, Ye; Zheng, Zai; Liu, Dong

    FRONTIERS IN PLANT SCIENCE

  • Functional and Structural Characterization of a Receptor-Like Kinase Involved in Germination and Cell Expansion in Arabidopsis

    Wu, Zhen; Liang, Shan; Song, Wen; Lin, Guangzhong; Wang, Weiguang; Zhang, Heqiao; Han, Zhifu; Chai, Jijie

    FRONTIERS IN PLANT SCIENCE

  • Functional characterization of human equilibrative nucleoside transporter 1

    Huang, Weiyun; Zeng, Xin; Shi, Yigong; Liu, Minhao

    PROTEIN & CELL

  • Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis

    Zhu, Bing; Zhu, Xin; Wang, Limei; Liang, Yinwen; Feng, Qianqian; Pan, Junmin

    PLOS GENETICS

  • Functional studies of Drosophila zinc transporters reveal the mechanism for zinc excretion in Malpighian tubules

    Yin, Sai; Qin, Qiuhong; Zhou, Bing

    BMC BIOLOGY

  • GDP-D-mannose epimerase regulates male gametophyte development, plant growth and leaf senescence in Arabidopsis

    Qi, Tiancong; Liu, Zhipeng; Fan, Meng; Chen, Yan; Tian, Haixia; Wu, Dewei; Gao, Hua; Ren, Chunmei; Song, Susheng; Xie, Daoxin

    SCIENTIFIC REPORTS

  • Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/beta-catenin signaling

    Zhang, Yu

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

  • Growth of B Cell Receptor Microclusters Is Regulated by PIP2 and PIP3 Equilibrium and Dock2 Recruitment and Activation

    Wang, Jing; Xu, Liling; Shaheen, Samina; Liu, Sichen; Zheng, Wenjie; Sun, Xiaolin; Li, Zhanguo; Liu, Wanli

    CELL REPORTS

  • HDAC6-mediated acetylation of lipid droplet-binding protein CIDEC regulates fat-induced lipid storage

    Qian, Hui; Chen, Yuanying; Nian, Zongqian; Su, Lu; Yu, Haoyong; Chen, Feng-Jung; Zhang, Xiuqin; Xu, Wenyi; Zhou, Linkang; Liu, Jiaming; Yu, Jinhai; Yu, Luxin; Gao, Yan; Zhang, Hongchao; Zhang, Haihong; Zhao, Shimin; Yu, Li; Xiao, Rui-Ping; Bao, Yuqian; Hou, Shaocong; Li, Pingping; Li, Jiada; Deng, Haiteng; Jia, Weiping; Li, Peng

    JOURNAL OF CLINICAL INVESTIGATION

  • Hippo kinases maintain polarity during directional cell migration in Caenorhabditis elegans

    Feng, Guoxin; Zhu, Zhiwen; Li, Wen-Jun; Lin, Qirong; Chai, Yongping; Dong, Meng-Qiu; Ou, Guangshuo

    EMBO JOURNAL

  • How cryo-electron microscopy and X-ray crystallography complement each other

    Wang, Hong-Wei; Wang, Jia-Wei

    PROTEIN SCIENCE

  • IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis

    Liu, Mingming; Ba, Zhaoqing; Costa-Nunes, Pedro; Wei, Wei; Li, Lanxia; Kong, Fansi; Li, Yan; Chai, Jijie; Pontes, Olga; Qi, Yijun

    PLANT CELL

  • IFT54 regulates IFT20 stability but is not essential for tubulin transport during ciliogenesis

    Zhu, Xin; Liang, Yinwen; Gao, Feng; Pan, Junmin

    CELLULAR AND MOLECULAR LIFE SCIENCES

  • ISG15 silencing increases cisplatin resistance via activating p53-mediated cell DNA repair

    Huo, Yi; Zong, Zhaoyun; Wang, Qingtao; Zhang, Zhenyu; Deng, Haiteng

    ONCOTARGET

  • Identification of high-confidence RNA regulatory elements by combinatorial classification of RNA-protein binding sites

    Li, Yang Eric; Xiao, Mu; Shi, Binbin; Yang, Yu-Cheng T.; Wang, Dong; Wang, Fei; Marcia, Marco; Lu, Zhi John

    GENOME BIOLOGY

  • Impairment of Cargo Transportation Caused by gbf1 Mutation Disrupts Vascular Integrity and Causes Hemorrhage in Zebrafish Embryos

    Chen, Jing; Wu, Xiaotong; Yao, Likun; Yan, Lu; Zhang, Lin; Qiu, Juhui; Liu, Xingfeng; Jia, Shunji; Meng, Anming

    JOURNAL OF BIOLOGICAL CHEMISTRY

  • Inter-adipocyte Adhesion and Signaling by Collagen IV Intercellular Concentrations in Drosophila

    Dai, Jianli; Ma, Mengqi; Feng, Zhi; Pastor-Pareja, Jose C.

    CURRENT BIOLOGY

  • Interplay between TGF-beta signaling and receptor tyrosine kinases in tumor development

    Shi, Qiaoni; Chen, Ye-Guang

    SCIENCE CHINA-LIFE SCIENCES

  • KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis

    Lin, Hao; Zhu, Xuechen; Chen, Geng; Song, Lei; Gao, Li; Khand, Aftab A.; Chen, Ying; Lin, Gufa; Tao, Qinghua

    DEVELOPMENT

  • LRFragLib: an effective algorithm to identify fragments for de novo protein structure prediction

    Wang, Tong; Yang, Yuedong; Zhou, Yaoqi; Gong, Haipeng

    BIOINFORMATICS

  • Learning shapes the aversion and reward responses of lateral habenula neurons

    Wang, Daqing; Li, Yi; Feng, Qiru; Guo, Qingchun; Zhou, Jingfeng; Luo, Minmin

    ELIFE

  • Mammalian mitochondrial RNAs are degraded in the mitochondrial intermembrane space by RNASET2

    Liu, Peipei; Huang, Jinliang; Zheng, Qian; Xie, Leiming; Lu, Xinping; Jin, Jie; Wang, Geng

    PROTEIN & CELL

  • Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure

    Liu, Xiaoyu; Li, Meijing; Xia, Xian; Li, Xueming; Chen, Zhucheng

    NATURE

  • Mechanism underlying berberine's effects on HSP70/TNF alpha under heat stress: Correlation with the TATA boxes

    Jiang Jing-Fei; Lei Fan; Yuan Zhi-Yi; Wang Yu-Gang; Wang Xin-Pei; Yan Xiao-Jin; Yu Xuan; Xing Dong-Ming; Du Li-Jun

    CHINESE JOURNAL OF NATURAL MEDICINES

  • Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme

    Li, Yini; Zhou, Mengying; Hu, Qi; Bai, Xiao-chen; Huang, Weiyun; Scheres, Sjors H. W.; Shi, Yigong

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  • Mechanistic insights into precursor messenger RNA splicing by the spliceosome

    Shi, Yigong

    NATURE REVIEWS MOLECULAR CELL BIOLOGY

  • Mechanistic insights into the alternative translation termination by ArfA and RF2

    Ma, Chengying; Kurita, Daisuke; Li, Ningning; Chen, Yan; Himeno, Hyouta; Gao, Ning

    NATURE

  • Metal-metal interaction mediates the iron induction of Drosophila MtnB

    Qiang, Wenjia; Huang, Yunpeng; Wan, Zhihui; Zhou, Bing

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

  • Microbial synthesis of a novel terpolyester P(LA-co-3HB-co-3HP) from low-cost substrates

    Ren, Yilin; Meng, Dechuan; Wu, Linping; Chen, Jinchun; Wu, Qiong; Chen, Guo-Qiang

    MICROBIAL BIOTECHNOLOGY

  • Mirror-image polymerase chain reaction

    Jiang, Wenjun; Zhang, Baochang; Fan, Chuyao; Wang, Min; Wang, Jiaxing; Deng, Qiang; Liu, Xianyu; Chen, Ji; Zheng, Jishen; Liu, Lei; Zhu, Ting F.

    CELL DISCOVERY

  • Mitochondria play an important role in the cell proliferation suppressing activity of berberine

    Yan, Xiao-Jin; Yu, Xuan; Wang, Xin-Pei; Jiang, Jing-Fei; Yuan, Zhi-Yi; Lu, Xi; Lei, Fan; Xing, Dong-Ming

    SCIENTIFIC REPORTS

  • Modelling of microbial polyhydroxyalkanoate surface binding protein PhaP for rational mutagenesis

    Zhao, Hongyu; Yao, Zhenyu; Chen, Xiangbin; Wang, Xinquan; Chen, Guo-Qiang

    MICROBIAL BIOTECHNOLOGY

  • Molecular Characterization of a Cytosolic Malate Dehydrogenase Gene(GhcMDH1) from Cotton

    Imran, Muhammad; Zhang Bing; Tang Kai; Liu Jinyuan

    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

  • Molecular architecture of the 90S small subunit pre-ribosome

    Sun, Qi; Zhu, Xing; Qu, Jia; An, Weidong; Lan, Pengfei; Tan, Dan; Chen, Rongchang; Wang, Bing; Zheng, Sanduo; Zhang, Cheng; Chen, Xining; Zhang, Wei; Chen, Jing; Dong, Meng-Qiu; Ye, Keqiong

    ELIFE

  • Molecular characterization of GhPLD alpha 1 and its relationship with se(c)ondary cell wall thickening in cotton fibers

    Tang, Kai; Liu, Jin-Yuan

    ACTA BIOCHIMICA ET BIOPHYSICA SINICA

  • Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE

    Ke, Meng; Yuan, Yafei; Jiang, Xin; Yan, Nieng; Gong, Haipeng

    PLOS COMPUTATIONAL BIOLOGY

  • Molecular dynamics study of ion transport through an open model of voltage-gated sodium channel

    Li, Yang; Sun, Ruining; Liu, Huihui; Gong, Haipeng

    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

  • Monomeric G-actin is uniformly distributed in pollen tubes and is rapidly redistributed via cytoplasmic streaming during pollen tube growth

    Chang, Ming; Li, Zhankun; Huang, Shanjin

    PLANT JOURNAL

  • Near-Atomic Resolution Structure Determination in Over-Focus with Volta Phase Plate by Cs-Corrected Cryo-EM

    Fan, Xiao; Zhao, Lingyun; Liu, Chuan; Zhang, Jin-Can; Fan, Kelong; Yan, Xiyun; Peng, Hai-Lin; Lei, Jianlin; Wang, Hong-Wei

    STRUCTURE

  • Novel T7-like expression systems used for Halomonas

    Zhao, Han; Zhang, Haoqian M.; Chen, Xiangbin; Li, Teng; Wu, Qiong; Ouyang, Qi; Chen, Guo-Qiang

    METABOLIC ENGINEERING

  • OPUS-DOSP: A Distance- and Orientation-Dependent All-Atom Potential Derived from Side-Chain Packing

    Xu, Gang; Ma, Tianqi; Zang, Tianwu; Sun, Weitao; Wang, Qinghua; Ma, Jianpeng

    JOURNAL OF MOLECULAR BIOLOGY

  • Organizational Innovation of Apical Actin Filaments Drives Rapid Pollen Tube Growth and Turning

    Qu, Xiaolu; Zhang, Ruihui; Zhang, Meng; Diao, Min; Xue, Yongbiao; Huang, Shanjin

    MOLECULAR PLANT

  • Overexpression of the transcription factor NF-YC9 confers abscisic acid hypersensitivity in Arabidopsis

    Bi, Chao; Ma, Yu; Wang, Xiao-Fang; Zhang, Da-Peng

    PLANT MOLECULAR BIOLOGY

  • POSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins

    Hu, Boqin; Yang, Yu-Cheng T.; Huang, Yiming; Zhu, Yumin; Lu, Zhi John

    NUCLEIC ACIDS RESEARCH

  • Plant Bax Inhibitor-1 interacts with ATG6 to regulate autophagy and programmed cell death

    Xu, Guoyong; Wang, Shanshan; Han, Shaojie; Xie, Ke; Wang, Yan; Li, Jinlin; Liu, Yule

    AUTOPHAGY

  • Plasma Heat Shock Protein 90alpha as a Biomarker for the Diagnosis of Liver Cancer: An Official, Large-scale, and Multicenter Clinical Trial

    Fu, Yan; Xu, Xiao; Huang, Dongsheng; Cui, Dawei; Liu, Lisheng; Liu, Junwei; He, Zenglei; Liu, Jingjing; Zheng, Shusen; Luo, Yongzhang

    EBIOMEDICINE

  • Predicting the helix-helix interactions from correlated residue mutations

    Xiong, Dapeng; Mao, Wenzhi; Gong, Haipeng

    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

  • Quantitative Analysis of Ligand Induced Heterodimerization of Two Distinct Receptors

    Lu, Chang; Wang, Zhi-Xin

    ANALYTICAL CHEMISTRY

  • RNA Regulations and Functions Decoded by Transcriptome-wide RNA Structure Probing

    Piao, Meiling; Sun, Lei; Zhang, Qiangfeng Cliff

    GENOMICS PROTEOMICS & BIOINFORMATICS

  • RNAe in a transgenic growth hormone mouse model shows potential for use in gene therapy

    Long, Haizhou; Yao, Yi; Jin, Shouhong; Yu, Yingting; Hu, Xiongbing; Zhuang, Fengfeng; Zhang, Hanshuo; Wu, Qiong

    BIOTECHNOLOGY LETTERS

  • RNase H1 Cooperates with DNA Gyrases to Restrict R-Loops and Maintain Genome Integrity in Arabidopsis Chloroplasts

    Yang, Zhuo; Hou, Quancan; Cheng, Lingling; Xu, Wei; Hong, Yantao; Li, Shuai; Sun, Qianwen

    PLANT CELL

  • Recent progress in autophagic lysosome reformation

    Chen, Yang; Yu, Li

    TRAFFIC

  • Recurrently deregulated lncRNAs in hepatocellular carcinoma

    Yang, Yang; Chen, Lei; Gu, Jin; Zhang, Hanshuo; Yuan, Jiapei; Lian, Qiuyu; Lv, Guishuai; Wang, Siqi; Wu, Yang; Yang, Yu-Cheng T.; Wang, Dongfang; Liu, Yang; Tang, Jing; Luo, Guijuan; Li, Yang; Hu, Long; Sun, Xinbao; Wang, Dong; Guo, Mingzhou; Xi, Qiaoran; Xi, Jianzhong; Wang, Hongyang; Zhang, Michael Q.; Lu, Zhi John

    NATURE COMMUNICATIONS

  • Ribosome Profiling Reveals Genome-wide Cellular Translational Regulation upon Heat Stress in Escherichia coli

    Zhang, Yanqing; Xiao, Zhengtao; Zou, Qin; Fang, Jianhuo; Wang, Qifan; Yang, Xuerui; Gao, Ning

    GENOMICS PROTEOMICS & BIOINFORMATICS

  • Role of TRIM33 in Wnt signaling during mesendoderm differentiation

    Xia, Xiaojie; Zuo, Feifei; Luo, Maoguo; Sun, Ye; Bai, Jianbo; Xi, Qiaoran

    SCIENCE CHINA-LIFE SCIENCES

  • SHIP-1 Deficiency in AID(+) B Cells Leads to the Impaired Function of B10 Cells with Spontaneous Autoimmunity

    Chen, Yingjia; Hu, Fanlei; Dong, Xuejiao; Zhao, Meng; Wang, Jing; Sun, Xiaolin; Kim, Tae Jin; Li, Zhanguo; Liu, Wanli

    JOURNAL OF IMMUNOLOGY

  • Screening of transporters to improve xylodextrin utilization in the yeast Saccharomyces cerevisiae

    Zhang, Chenlu; Acosta-Sampson, Ligia; Yu, Vivian Yaci; Cate, Jamie H. D.

    PLOS ONE

  • Serine phosphorylation of the cotton cytosolic pyruvate kinase GhPK6 decreases its stability and activity

    Zhang, Bing; Liu, Jin-Yuan

    FEBS OPEN BIO

  • Simulating the Activation of Voltage Sensing Domain for a Voltage-Gated Sodium Channel Using Polarizable Force Field

    Sun, Rui-Ning; Gong, Haipeng

    JOURNAL OF PHYSICAL CHEMISTRY LETTERS

  • Single-Molecule Photoactivation FRET: A General and Easy-To-Implement Approach To Break the Concentration Barrier

    Peng, Sijia; Sun, Ruirui; Wang, Wenjuan; Chen, Chunlai

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

  • Spatiotemporal expression profiling of long intervening noncoding RNAs in Caenorhabditis elegans

    Liu, Weihong; Yu, Enchao; Chen, Siyu; Ma, Xiaopeng; Lu, Yiwen; Liu, Xiao

    SCIENTIFIC REPORTS

  • Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion

    Yang, Yihong; Zhang, Yan; Li, Wen-Jun; Jiang, Yuxiang; Zhu, Zhiwen; Hu, Huifang; Li, Wei; Wu, Jia-Wei; Wang, Zhi-Xin; Dong, Meng-Qiu; Huang, Shanjin; Ou, Guangshuo

    DEVELOPMENTAL CELL

  • Structural Insights of WHAMM's Interaction with Microtubules by Cryo-EM

    Liu, Tianyang; Dai, Anbang; Cao, Yong; Zhang, Rui; Dong, Meng-Qiu; Wang, Hong-Wei

    JOURNAL OF MOLECULAR BIOLOGY

  • Structural and Dynamic Insights into the Mechanism of Allosteric Signal Transmission in ERK2-Mediated MKP3 Activation

    Lu, Chang; Liu, Xin; Zhang, Chen-Song; Gong, Haipeng; Wu, Jia-Wei; Wang, Zhi-Xin

    BIOCHEMISTRY

  • Structural basis for receptor recognition of pollen tube attraction peptides

    Zhang, Xiaoxiao; Liu, Weijia; Nagae, Takuya T.; Takeuchi, Hidenori; Zhang, Heqiao; Han, Zhifu; Higashiyama, Tetsuya; Chai, Jijie

    NATURE COMMUNICATIONS

  • Structural insights into ligand recognition and activation of plant receptor kinases

    Song, Wen; Han, Zhifu; Wang, Jizong; Lin, Guangzhong; Chai, Jijie

    CURRENT OPINION IN STRUCTURAL BIOLOGY

  • Structural insights into the secretin translocation channel in the type II secretion system

    Yan, Zhaofeng; Yin, Meng; Xu, Dandan; Zhu, Yongqun; Li, Xueming

    NATURE STRUCTURAL & MOLECULAR BIOLOGY

  • Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1

    Ma, Chengying; Wu, Shan; Li, Ningning; Chen, Yan; Yan, Kaige; Li, Zhifei; Zheng, Lvqin; Lei, Jianlin; Woolford, John L., Jr.; Gao, Ning

    NATURE STRUCTURAL & MOLECULAR BIOLOGY

  • Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution

    Shen, Huaizong; Zhou, Qiang; Pan, Xiaojing; Li, Zhangqiang; Wu, Jianping; Yan, Nieng

    SCIENCE

  • Structure of a yeast step II catalytically activated spliceosome

    Yan, Chuangye; Wan, Ruixue; Bai, Rui; Huang, Gaoxingyu; Shi, Yigong

    SCIENCE

  • Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae

    Wan, Ruixue; Yan, Chuangye; Bai, Rui; Lei, Jianlin; Shi, Yigong

    CELL

  • Structure of phycobilisome from the red alga Griffithsia pacifica

    Zhang, Jun; Ma, Jianfei; Liu, Desheng; Qin, Song; Sun, Shan; Zhao, Jindong; Sui, Sen-Fang

    NATURE

  • Structure of the Human Lipid Exporter ABCA1

    Qian, Hongwu; Zhao, Xin; Cao, Pingping; Lei, Jianlin; Yan, Nieng; Gong, Xin

    CELL

  • Structure of the Na(v)1.4-beta 1 Complex from Electric Eel

    Yan, Zhen; Zhou, Qiang; Wang, Lin; Wu, Jianping; Zhao, Yanyu; Huang, Gaoxingyu; Peng, Wei; Shen, Huaizong; Lei, Jianlin; Yan, Nieng

    CELL

  • Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae

    Bai, Rui; Yan, Chuangye; Wan, Ruixue; Lei, Jianlin; Shi, Yigong

    CELL

  • Structure-based assessment of disease-related mutations in human voltage-gated sodium channels

    Huang, Weiyun; Liu, Minhao; Yan, S. Frank; Yan, Nieng

    PROTEIN & CELL

  • Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKC beta and focal adhesion kinase

    Shaheen, Samina; Wan, Zhengpeng; Li, Zongyu; Chau, Alicia; Li, Xinxin; Zhang, Shaosen; Liu, Yang; Yi, Junyang; Zeng, Yingyue; Wang, Jing; Chen, Xiangjun; Xu, Liling; Chen, Wei; Wang, Fei; Lu, Yun; Zheng, Wenjie; Shi, Yan; Sun, Xiaolin; Li, Zhanguo; Xiong, Chunyang; Liu, Wanli

    ELIFE

  • Synthesis of Medium-Chain-Length Polyhydroxyalkanoate Homopolymers, Random Copolymers, and Block Copolymers by an Engineered Strain of Pseudomonas entomophila

    Wang, Ying; Chung, Ahleum; Chen, Guo-Qiang

    ADVANCED HEALTHCARE MATERIALS

  • TRPM8 in the negative regulation of TNF alpha expression during cold stress

    Wang, Xin-Pei; Yu, Xuan; Yan, Xiao-Jin; Lei, Fan; Chai, Yu-Shuang; Jiang, Jing-Fei; Yuan, Zhi-Yi; Xing, Dong-Ming; Du, Li-Jun

    SCIENTIFIC REPORTS

  • Tango1 spatially organizes ER exit sites to control ER export

    Liu, Min; Feng, Zhi; Ke, Hongmei; Liu, Ying; Sun, Tianhui; Dai, Jianli; Cui, Wenhong; Pastor-Pareja, Jose Carlos

    JOURNAL OF CELL BIOLOGY

  • Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria

    Yang, Yiqing; Yu, You; Li, Xiaolu; Li, Jing; Wu, Yue; Yu, Jie; Ge, Jingpeng; Huang, Zhenghui; Jiang, Lubin; Rao, Yu; Yang, Maojun

    JOURNAL OF MEDICINAL CHEMISTRY

  • The Membrane-Proximal Region of C-C Chemokine Receptor Type 5 Participates in the Infection of HIV-1

    Tan, Yue; Tong, Pei; Wang, Junyi; Zhao, Lei; Li, Jing; Yu, Yang; Chen, Ying-Hua; Wang, Ji

    FRONTIERS IN IMMUNOLOGY

  • The R-loop is a common chromatin feature of the Arabidopsis genome

    Xu, Wei; Xu, Hui; Li, Kuan; Fan, Yingxu; Liu, Yang; Yang, Xuerui; Sun, Qianwen

    NATURE PLANTS

  • The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus

    Zhu, Xuechen; Xing, Rui; Tan, Renbo; Dai, Rongyang; Tao, Qinghua

    MECHANISMS OF DEVELOPMENT

  • The Sec14-like phosphatidylinositol transfer proteins Sec1413/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

    Gong, Bo; Shen, Weimin; Xiao, Wenghua; Meng, Yaping; Meng, Anming; Jia, Shunji

    ELIFE

  • The Spliceosome: A Protein-Directed Metalloribozyme

    Shi, Yigong

    JOURNAL OF MOLECULAR BIOLOGY

  • The antimalarial drug artemisinin induces an additional, Sod1-supressible anti-mitochondrial action in yeast

    Sun, Chen; Zhou, Bing

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

  • The crystal structure of Ac-AChBP in complex with alpha-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes

    Xu, Manyu; Zhu, Xiaopeng; Yu, Jinfang; Yu, Jinpeng; Luo, Sulan; Wang, Xinquan

    PROTEIN & CELL

  • The receptor genes PfBMPR1B and PfBAMBI are involved in regulating shell biomineralization in the pearl oyster Pinctada fucata

    Li, Shiguo; Liu, Yangjia; Huang, Jingliang; Zhan, Aibin; Xie, Liping; Zhang, Rongqing

    SCIENTIFIC REPORTS

  • The size matters: regulation of lipid storage by lipid droplet dynamics

    Yu, Jinhai; Li, Peng

    SCIENCE CHINA-LIFE SCIENCES

  • Total chemical synthesis of a thermostable enzyme capable of polymerase chain reaction

    Xu, Weiliang; Jiang, Wenjun; Wang, Jiaxing; Yu, Linping; Chen, Ji; Liu, Xianyu; Liu, Lei; Zhu, Ting F.

    CELL DISCOVERY

  • Transcription Factor Antagonism Controls Enteroendocrine Cell Specification from Intestinal Stem Cells

    Li, Yumei; Pang, Zhimin; Huang, Huanwei; Wang, Chenhui; Cai, Tao; Xi, Rongwen

    SCIENTIFIC REPORTS

  • Versatile DNA Origami Nanostructures in Simplified and Modular Designing Framework

    Cui, Yan; Chen, Ruipeng; Kai, Mingxuan; Wang, Yaqi; Mi, Yongli; Wei, Bryan

    ACS NANO

  • Viral effector protein manipulates host hormone signaling to attract insect vectors

    Wu, Dewei; Qi, Tiancong; Li, Wan-Xiang; Tian, Haixia; Gao, Hua; Wang, Jiaojiao; Ge, Jin; Yao, Ruifeng; Ren, Chunmei; Wang, Xian-Bing; Liu, Yule; Kang, Le; Ding, Shou-Wei; Xie, Daoxin

    CELL RESEARCH

  • WASP-Arp2/3-dependent actin polymerization influences fusogen localization during cell-cell fusion in Caenorhabditis elegans embryos

    Zhang, Yan; Yang, Yihong; Zhu, Zhiwen; Ou, Guangshuo

    BIOLOGY OPEN

  • WSF-P-1, a novel AMPK activator, promotes adiponectin multimerization in 3T3-L1 adipocytes

    Wang, Yao; Zhang, Yudian; Wang, Yunyun; Peng, Han; Rui, Jian; Zhang, Zhijie; Wang, Shifa; Li, Zhen

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

  • Zebrafish cdc6 hypomorphic mutation causes Meier-Gorlin syndrome-like phenotype

    Yao, Likun; Chen, Jing; Wu, Xiaotong; Jia, Shunji; Meng, Anming

    HUMAN MOLECULAR GENETICS

  • pBACode: a random-barcode-based high-throughput approach for BAC paired-end sequencing and physical clone mapping

    Wei, Xiaolin; Xu, Zhichao; Wang, Guixing; Hou, Jilun; Ma, Xiaopeng; Liu, Haijin; Liu, Jiadong; Chen, Bo; Luo, Meizhong; Xie, Bingyan; Li, Ruiqiang; Ruan, Jue; Liu, Xiao

    NUCLEIC ACIDS RESEARCH

  • txCoords: A Novel Web Application for Transcriptomic Peak Re-Mapping

    Yan, Zhangming; Liu, Ke; Xiang, Shunian; Sun, Zhirong

    IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS

  • Dominant negative effect of the loss-of-functionγ-secretase mutants on the wild-type enzyme through heterooligomerization.

    Rui Zhou#, Guanghui Yang#, and Yigong Shi*.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  • Influencing Mechanism of Ocean Acidification on Byssus Performance in the Pearl Oyster Pinctada fucata

    Li, Shiguo; Liu, Chuang; Xie, Liping; Zhang, Rongqing; Zhan, Aibin

    Environmental Science and Technology

  • Membrane Trafficking in Plant Immunity

    Yangnan Gu, Raul Zavaliev and Xinnian Dong

    Molecular Plant