朱听 博士

研究员,博士生导师

1999.9-2003.1 清华大学工程力学系    学士,优秀毕业生、提前毕业
2003.9-2005.9 麻省理工学院(MIT)机械工程系    硕士
2005.9-2010.6 哈佛-麻省理工健康科学与技术 (Harvard-MIT Health Sciences and Technology)    博士
2010.7-2011.9 麻省理工学院(MIT)/哈佛医学院麻省总医院(MGH)    博士后
2011.9-至今      清华大学生命科学学院     研究员,博士生导师

● 研究兴趣、领域:

镜像生物学系统、化学生物学


实验室网站:http://zhulab.life.tsinghua.edu.cn


● 代表性论文:

1. Liu X, Zhu TF*. Sequencing mirror-image DNA chemically. Cell Chemical Biology, 25:1-6, (2018).

2. Wang G#, Du M#, Wang J*, Zhu TF*. Genetic variation may confound analysis of CRISPR-Cas9 off-target mutations. Cell Discovery, 4:18, (2018).

3. Kayani MU#, Doyle SM#, Sangwan N, Wang G, Gilbert JA*, Christner BC*, Zhu TF*. Metagenomic analysis of basal ice from an Alaskan glacier. Microbiome, 6:123, (2018).

4. Jiang W#, Zhang B#, Fan C#, Wang M#, Wang J, Deng Q, Liu X, Chen J, Zheng J, Liu L*, Zhu TF*. Mirror-image polymerase chain reaction. Cell Discovery, 3:17037, (2017).

5. Pontefract A, Zhu TF, Walker VK, Hepburn H, Lui C, Zuber MT, Ruvkun G, Carr CE*. Microbial diversity in a hypersaline sulfate lake: a terrestrial analog of ancient Mars. Frontiers in Microbiology, 8:1819, (2017).

6. Xu W#, Jiang W#, Wang J#, Yu L#, Chen J, Liu X, Liu L*, Zhu TF*. Total chemical synthesis of a thermostable enzyme capable of polymerase chain reaction. Cell Discovery, 3:17008, (2017).

7. Su HW#, Zhu JH#, Li H, Cai RJ, Ealand C, Wang X, Chen YX, Kayani MU, Zhu TF, Moradigaravand D, Huang H, Kana BD, Javid B*. The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity. Nature Microbiology, 1:16147, (2016).

8. Wang Z#, Xu W#, Liu L*, Zhu TF*. A synthetic molecular system capable of mirror-image genetic replication and transcription. Nature Chemistry, 8(7):698-704, (2016). (Highlighted by Nature [PDF], Scientific American, C&EN News, and F1000Prime)

9. Jiang W*, Zhu TF*. Targeted isolation and cloning of 100-kb microbial genomic sequences by Cas9-assisted targeting of chromosome segments. Nature Protocols, 11(5):960-975, (2016).

10. Jiang W, Zhao X, Gabrieli T, Lou C*, Ebenstein Y*, Zhu TF*. Cas9-Assisted Targeting of CHromosome segments CATCH enables one-step targeted cloning of large gene clusters. Nature Communications, 6:8101, (2015).

11. Zheng Y#, Kayani MU#, Zhu TF*. Rapid identification of multi-strain HBV infection in patient by high-throughput DNA sequencing. Quantitative Biology, 3(2):103-106, (2015).

12. Jiang W, Liang P, Wang B, Fang J, Lang J, Tian G, Jiang J, Zhu TF*. Optimized DNA extraction and metagenomic sequencing of airborne microbial communities. Nature Protocols, 10(5):768-779, (2015).

13. Cao C, Jiang W#, Wang B#, Fang J, Lang J, Tian G*, Jiang J*, and Zhu TF*. Inhalable microorganisms in Beijing’s PM2.5 and PM10 pollutants during a severe smog event. Environmental Science & Technology, 48(3):1499-1507, (2014). (Web of Science ‘Highly Cited Paper’: top 1% of the field; Highlighted by Nature, Scientific American, Popular Science, The Scientist, Los Angeles Times, and Business Insider)

*Corresponding author(s)

#Equal  contributions

 

● 联系方式:

清华大学生命科学学院

生物技术馆4-201
北京100084
电话: +86-10-62797325
Email: tzhu@tsinghua.edu.cn