陈国强 博士

教授,博士生导师,长江学者特聘教授,国家杰出青年基金获得者

1981-1985  广州华南理工大学,学士

1986-1989  奥地利格拉茨工业大学,博士

1990-1992  英国诺丁汉大学,博士后

1992-1994  加拿大阿尔伯达大学,博士后

1994-1997  清华大学生命科学学院,副教授

1997-至今  清华大学生命科学学院,教授、博导

 

● 研究兴趣、领域:

合成生物学、微生物代谢工程、生物材料、工业生物技术

● 代表性论文:

1.      Zhao Han, Zhang Haoqian M, Li Teng, Lou Chunbo, Ouyang Qi and Chen GQ. Novel T7-Like Expression Systems Used for Halomonas. Metabolic Engineering 39 (2017) 128-140

2.      Elhadi Dina, Lv Li, Jiang Xiaoran, Wu Hong and Chen GQ. CRISPRi Engineering E. coli for Morphology Diversification. Metabolic Engineering 38 (2016) 358-369

3.      Jiang Xiaoran and Chen GQ. Morphology Engineering of Bacteria for Bio-production Biotechnology Advances 34 (2016) 435–440

4.      Chen GQ and Hajnal Ivan. The “PHAome”. Trends in Biotechnology 33 (2015) 559-564

5.        Jiang Xiaoran, Wang Huan, Shen Rui and Chen GQ.  Engineering the Bacterial Shapes for Enhanced Inclusion Bodies Accumulation. Metabolic Engineering 29 (2015) 227-237

6.      Lv Li, Ren Yilin, Chen Jin Chun, Wu Qiong and Chen GQ. Application of CRISPRi for Prokaryotic Metabolic Engineering Involving Multiple Genes, A Case Study: Controllable P(3HB-co-4HB) Biosynthesis. Metabolic Engineering 29 (2015) 160–168

7.      Yin Jin, Chen Jinchun, Wu Qiong and Chen GQ. Halomonas spp, a Rising Star for Industrial Biotechnology. Biotechnology Advance 33 (2015) 1433-1442

8.      Tan Dan, Wu Qiong, Chen, Jin-Chun and Chen GQ. Engineering Halomonas TD01 for Low Cost Production of Polyhydroxyalkanoates. Metabolic Engineering 26 (2014) 34–47

9.      Wang Ying, Wu Hong, Jiang Xiaoran and Chen GQ. Engineering Escherichia coli for Enhanced Production of Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Larger Cellular Space. Metabolic Engineering 25 (2014) 183-193

10.    Wang Y, Yin Jin and Chen GQ. Microbial Polyhydroxyalkanoates, Challenges and Opportunities. Current Opinion in Biotechnology 30 (2014) 59-65 

11.    Chen GQ, Jiang XR. Engineering microorganisms for improving polyhydroxyalkanoate biosynthesis. Current Opinion in Biotechnology 53 (2018) 20-25

12.    Ouyang PF, Wang H, Hajnal I, Wu Q. Guo YY, Chen GQ*. Increasing oxygen availability for improving PHB production by Halomonas. Metabolic Engineering 45 (2018) 20-31

13.    Zhang XC, Guo YY, Liu X, Chen XG, Wu Q, Chen GQ*. Engineering cell wall synthesis mechanism for enhanced PHB accumulation in E. coli. Metabolic Engineering 45 (2018)

14.    Chen GQ*, Jiang XR. Next generation industry biotechnology based on exremophiles. Current Opinion in Biotechnology 50 (2018) 94-100

15.    Zhao H, Zhang HQ M, Li T, Lou CB, Ouyang Q.  Chen GQ*. Novel T7-Like expression systems used for Halomonas. Metabolic Engineering 39 (2017) 128-140

16.    Li T, Elhadi D, Chen GQ*. Co-production of microbial polyhydroxyalkanoates with other chemicals. Metabolic Engineering 43 (2017) 29-36

17.    Jiang XR, Yao ZH, Chen GQ*. Controllable Mmorphology engineering Halomonas for efficient PHB production. Metabolic Engineering 44C (2017) 30-37

18.    Elhadi D, Lv L, Jiang XR, Wu H, Chen GQ*. CRISPRi engineering E. coli for morphology diversification. Metabolic Engineering 38 (2016) 358-369

19.    Chen GQ*, Hajnal I, Ma YM, Wu H, Ye JW. Engineering the bacterial synthesis mechanism for diversifying polyhydroxyalkanoates. Trends in Biotechnology 33 (2015) 565-574

 

● 联系方式:

电话:010-62783844(office)     010-62772676(lab)

邮箱:chengq@tsinghua.edu.cn