Xianming PAN, Ph.D.


Winner of the National Science Foundation for Outstanding Young Scientists of China 1978-1981,
B.S, Fudan University, Shanghai, China 1982-1984,
M.S, Peking University, Beijing, China 1986--1989,
 PhD, Ruhr University, Bochum, Germany Professor of Tsinghua University

Research interest

Biochemistry, Molecular Biophysics, protein folding, protein structure prediction

Selected publications

  • Sheng X. R., Zhang H. J., Pan X. M. and Zhou J.M. (1997) Domain movement in rabbit muscle adenylate kinase might involve proline isomerization. FEBS Letters, 413, 429-432.
  • Zhang H. J., Sheng X. R., Pan X. M.* and Zhou J.M. (1997) Activation of adenylate kinase by denaturatants is due to the increasing flexibility at its active sites. BBRC, 238, 382-386.
  • Zhang H. J., Sheng X. R., Niu W. D., Pan X. M.* and Zhou J.M. (1998) Rabbit Muscle Adenylate Kinase: Evidence for at Least Two Native forms in Equilibrium in Aqueous Solution. J. Biol. Chem., 273, 7448-7456.
  • Zhang H. J., Sheng X. R., Pan X. M.* and Zhou J. M. (1998) Refolding of urea-denatured adenylate kinase. Biochem. J., 333, 401-405.
  • Sheng X. R., Li X. and Pan X. M.* (1999) An Iso-random Bi Bi mechanism for adenylate kinase. J. Biol. Chem., 274, 22238-22243.
  • Li X. and Pan X. M.* (2001) New Method for accurate prediction of solvent accessibility from protein sequence. Proteins, structure, Function, and Genetics, 42, 1-5.
  • Pan X. M.* (2001) Multiple linear regression for protein secondary structure prediction. Proteins, structure, Function, and Genetics. 43,256-9
  • Li X., Yang Han and Pan X. M.*(2001) Cysteine-25 of adenylate kinase reacts with dithiothreitol to form an adduct upon aging of the enzyme. FEBS Letters, 507 (2) 169-173.
  • Han Y. , Li X. and Pan X. M.*(2002) Native States of adenylate kinase are two active sub-ensembles. FEBS Letter, 528 161-165
  • Xu S., Qin S. and Pan X. M.* (2004)Thermal and Conformational Stability of Ssh10b Protein from Archaeon Sulfolobus shibattae. Biochem. J, 382, 433-440.
  • Nan Zhang, Xian-Ming Pan*, Meng Ge*. Without salt, the ‘thermophilic’ protein mth10b is just mesophilic. PLoS ONE, 2012, 7(12):e53125.
  • Jing Yang, Meng Ge, Xian-Ming Pan*. A time lag insensitive approach for estimating HIV-1 transmission direction. AIDS, 2012, 26(8): 921-928.
  • Jing Yang, Xia-Yu Xia, Xiang He, Sen-Lin Yang, Yu-Hua Ruan, Quan-Bi Zhao, Zhi-Xin Wang, Yi-Ming Shao, Xian-Ming Pan*. A new pattern-based method for identifying recent HIV-1 infections from the viral sequence. SCIENCE CHINA-LIFE SCIENCES, 2012, 55 (4): 328-335.
  • Yan-Feng Liu, Nan Zhang, Xi Liu, Xin-Quan Wang, Zhi-Xin Wang, Yuan-Yuan Chen, Hong-Wei Yao, Meng Ge, Xian-Ming Pan*. Molecular Mechanism Underlying the Interaction of Typical Sac10b Family Proteins with DNA. PLoS ONE, 2012, 7(4): e34986.
  • Xia-Yu Xia, Meng Ge, Zhi-Xin Wang, Xian-Ming Pan*. Accurate Prediction of Protein Structural Class. PLoS ONE, 2012, 7(6): e37653.


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