Rongqing ZHANG

Rongqing Zhang Ph.D. Professor

1982,    B.M. Suzhou Medicine College

1993,    Ph.D. Nanjing Agricultural University

1995,    Postdoc, State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Science

Since 1998, Professor of Tsinghua University

Since 2009, Vice Dean of School of Life Sciences

1996-2004, Senior member of Expert Committee of National High Technology Research and Development Program (863) in Marine Biotechnology

2007-present, Member of the Expert Advisory Committee of National Basic Research Program of China (973 Program) in Agriculture

Director of the Institute of Marine Biotechnology, School of Life Sciences, Tsinghua University

Member of European Society for Marine Biotechnology (ESMB) and Editorial Board of Marine Biotechnology

2016-present  Department of Biotechnology and Biomedicine, Yangtze Delta Region Institute of Tsinghua University  Institute director


Research interest

Marine biochemistry and molecular biology, focusing on detecting new functional genes from marine creatures. Molecular mechanisms of marine biomineralization. Publishing over 70 SCI papers in recent years.

Selected publications

[1]Pan C, Fang D., Xu GR, Liang J, Zhang G., Wang, HZ, Xie LP, Zhang RQ. A novel acidic matrix protein, PfN44, stabilizes the magnesium calcite to inhibit the crystallization of aragonite. Journal of Biological Chemistry, 2014, 289(5): 2776-2787.

[2]Su JT, Liang X, Zhou Q, Zhang GY, Wang HZ, Xie LP, Zhang RQ. Structural characterization of amorphous calcium carbonate-binding protein: an insight into the mechanism of amorphous calcium carbonate formation. Biochemical Journal, 2013, 453: 179-186

[3]Liu XJ, Li J, Xiang L, Zhang RQ. The role of matrix proteins in the control of nacreous layer deposition during pearl formation. Proceedings of the Royal Society B: Biological Sciences, 2012, 279(1730): 1000-1007

[4]Fang D, Pan C, Zhang RQ. Novel Basic Protein, PfN23, Functions as key macromolecule during nacre formation. Journal of Biological Chemistry, 2012, 287(19): 15776-85

[5]Kong YW, Jing G, Yan ZG, Li CZ, Gong NP, Zhu FJ, Li DX, Zhang YR, Zheng GL, Wang HZ, Xie LP, Zhang RQ. Cloning and Characterization of Prisilkin-39, a novel matrix protein serving a dual role in the prismatic layer formation from the oyster Pinctada fucata. Journal of Biological Chemistry, 2009, 284: 10841-10854

[6] Yan ZG, Jing G, Gong NP, Li CZ, Zhou YJ, Xie LP, Zhang RQ. N40, a novel nonacidic matrix protein from pearl oyster nacre facilitates nucleation of aragonite in vitro. Biomacromolecules, 2007, 8:3597-3601

[7] Ma ZJ, Huang J, Sun J, Wang GN, Li CZ, Xie LP, Zhang RQ. A novel extrapallial fluid protein controls the morphology of nacre lamellae in the pearl oyster, Pinctada fucata. Journal of Biological Chemistry, 2007, 282(32):23253-23263

[8] Li SG, Liu C, Zhan AB, Xie LP, Zhang RQ. Influencing mechanism of Ocean acidification on byssus performance in the pearl oyster Pinctada fucata. Environ. Sci. Technol. 2017, 51 (13), 7696–7706.

[9] Liu C, Du JZ, Xie LP, Zhang RQ. Direct observation of nacre proteins in the whole calcite by super resolution microscopy reveals diverse occlusion patterns. Cryst. Growth Des. 2017,4:1966?1976.

[10] Yan Y, Yang D, Yang X, Liu C; Xie J, Zheng GL, Xie LP, Zhang RQ. A novel matrix protein, PfY2, functions as a crucial macromolecule during shell formation. Sci Rep. 2017; 7: 6021.

[11] Gao J, Chen Y, Yang Y, Liang J, Xie J, Liu, Li SG, Zheng GL, Xie LP, Zhang RQ. The transcription factor Pf-POU3F4 regulates expression of the matrix protein genes Aspein and Prismalin-14 in pearl oyster (Pinctada fucata). FEBS J, 2016, 283(10):1962-78.

[12] Xie J, Liang J, Sun J, Gao J, Zhang SR, Liu YJ, Xie LP, Zhang RQ. Influence of the Extrapallial Fluid of Pinctada fucata on the Crystallization of Calcium Carbonate and Shell Biomineralization. Cryst. Growth Des. 2016,16:672?680.

[13] Liu C, Xie LP, Zhang RQ. Ca2+ Mediates the Self-Assembly of the Foot Proteins of Pinctada fucata from the Nanoscale to the Microscale. Biomacromolecules, 2016, 17 (10): 3347–3355.

[14] Liu J, Yang D, Liu ST, Li SG, Xu GR, Zheng GL, Xie LP, Zhang RQ. Microarray: a global analysis of biomineralization-related gene expression profiles during larval development in the pearl oyster, Pinctada fucata. BMC Genomics, 2015, 16(1): 325.


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