Jinchun CHEN

Associate Professor


1987-1992, B.S.,  Tsinghua University

1992-1995, M.S.,  Tsinghua University 

 

1995-1997, Tutor in the DBSB, Tsinghua University

1996-1997, Research Assistant in ABCT, HongKong Polytechnic U

1997-2005, Lecturer in the DBSB, Tsinghua University

2005-present,  Associate Professor for School of Life Sciences, Tsinghua University

 

Research interest


Industrial Microbiology and Biological Chemical Engineering. Focus on biotransformation of chemical intermediate, synthesis and application of new biomaterial and special macromolecular material. 

Selected publications


  • Ah-Leum Chung#, Guo-Dong Zeng#, Hong-Liang Jin, Qiong Wu, Jin-Chun Chen*, Guo-Qiang Chen*. Production of medium-chain-length 3-hydroxyalkanoic acids by beta-oxidation and phaC operon deleted Pseudomonas entomophila harboring thioesterase gene. Metabolic Engineering 2013,17 :23–29.

  • Xiao-Yun Zhou#, Xiao-Xi Yuan#, Zhen-Yu Shi, De-Chuang Meng, Wen-Jun Jiang, Lin-Ping Wu, Jin-Chun Chen* and Guo-Qiang Chen*. Hyperproduction of poly(4-hydroxybutyrate) from glucose by recombinant Escherichia coliMicrobial Cell Factories. 2012, 11:54-61

  • Hu D, Zheng M, Zhang X, Wu Q, Chen JC* and Chen GQ*. Biosynthesis and Characterization of Polyhydroxyalkanoate Block Copolymer P3HB-b-P4HB. Biomacromolecules . 2011,12: 3166-3173

  • Zhou Q, Shi ZY, Meng DC, Wu Q, Chen JC* and Chen GQ*. Production of 3-Hydroxypropionate Homopolymer and Poly(3-Hydroxypropionate-co- 4-hydroxybutyrate) Copolymer by Recombinant Escherichia coliMetabolic Engineering.  2011,13:777–785

  • Sun SY, Zhang X, Zhou Q, Chen Jin-Chun*, Chen GQ*. Microbial production of cis-1,2-dihydroxy-cyclohexa-3,5-diene-1-carboxylate by genetically modified Pseudomonas putida. Appl Microbiol Biotechnol.2008, 80:977-984

  • Ouyang SP, Liu Q, Sun SY, Chen Jin-Chun, Chen GQ. Genetic engineering of Pseudomonas putida KT2442 for biotransformation of aromatic compounds to chiral cis-diols. Journal of Biotechnology 2007, 132: 246–250

  • Wang YW, Wu Q, Chen Jin-Chun, Chen GQ  Evaluation of three-dimensional scaffolds made of blends of hydroxyapatite and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for bone reconstruction. Biomaterials. 2005. 26(8): 899-904.

  • Zheng Z; Gong Q; Liu T; Deng Y; Chen Jin-Chun; Chen GQ. Thioesterase II of Escherichia coli plays an important role in 3-hydroxydecanoic acid production. Applied and Environmental Microbiology. 2004, 70 (7): 3807-3813.

  • Chen JY; Liu T; Zheng Z; Chen Jin-Chun, Chen GQ. Polyhydroxyalkanoate synthases PhaC1 and PhaC2 from Pseudomonas stutzeri 1317 had different substrate specificities. FEMS Microbiology Letters. 2004. 234(2): 231-237.

  • Zhou XY, Yuan XX, Shi ZY, Meng DC, Jiang WJ, Wu LP, Chen JC* and Chen GQ*.(2012)Hyperproduction of poly(4-hydroxybutyrate) from glucose by recombinant Escherichia coli. Microbial Cell Factories. 11:54-61.


Textbooks:

  • Experimental Instruction for Fundamental Life Science (2009)

  • Bioreaction Engineering Principles(2011)

  • Experimental Instruction for Microbiology (2005, 2007)

  • Experimental Instruction for Modern Biology(1999)

 

Awards


  • 1st Class, Production and Applied Research on Bioplastics(PHBHHx), Progress Award of Science and Technology, Beijing, China(2001)

  • 2nd Class, Production and Development of Bioplastics(PHBHHx)National Technology ­­Invention Award, China (2002)

  • Silver Prize,Bioplastics,the 2003 Nuremberg new ideas, new inventions, new products exhibition, Germany

  • 2nd Class, Basic Applied Research on Microbial Polyhydroxyalkanoate (PHA), Progress Award of Science and Technology, Beijing, China (2012)



Contact information


Lab of Microbiology, School of Life Sciences, Tsinghua University, Beijing 100084, China

Tel (Fax): +86-10-62788784

E-mail: chenjc@mail.tsinghua.edu.cn