教职员工
兼职教授
讲席教授
杰出人才
其他获奖
刘玉乐

 

刘玉乐 博士
教授,百人教授,国家杰出青年基金获得者,博士生导师

教育经历:
1984.9-1988.7         天津南开大学生物化学专业 (学士)          
1990.9-1992.6         北京中国科学院微生物学研究所 (硕士)    
1994.9-1997.11       中国科学院微生物学研究所与英国苏格兰作物研究所联合培养博士

学术简历:
1988.8-1998.9         北京中国科学院微生物学研究所   实习,助理,副研究员,研究员
1995.5-1996.5         英国苏格兰作物研究所                访问学者
1998.9-1999.8         美国德克萨斯大学奥斯丁分校      博士后
1999.9-2002.8         美国耶鲁大学                       博士后
2002.9-2006.12       美国耶鲁大学                       Associate Research Scientist
2007.1 ---至今         清华大学                              教授,“百人计划”责任教授

研究方向:
植物免疫的信号传导与调控、植物病毒病理的分子基础、植物细胞自噬、植物功能基因组

学术荣誉:
1997年,中国科学院青年科学家奖获得者
2007年,国家杰出青年基金获得者
2007年,清华大学“百名人才引进计划” 责任教授

代表性论文:

1.     Liu N, Xie K, Jia Q, Zhao J, Chen T, Li H, Wei X, Diao X, Hong Y and Liu Y*, Foxtail Mosaic Virus-Induced Gene Silencing in Monocot Plants, Plant Physiology, 2016 May 25. pii: pp.00010.2016

2.     Jia Q, Liu N, Xie K, Dai Y, Han S, Zhao X, Qian L, Wang Y, Zhao J, Gorovits R, Xie D, Hong Y and Liu Y*, CLCuMuB βC1 Subverts Ubiquitination by Interacting with NbSKP1s to Enhance Geminivirus Infection in Nicotiana benthamiana, PLoS Pathogens, 12(6): e1005668, 2016

3.     Zhao J*, Liu Q, Hu P, Jia Q, Liu N, Yin K, Cheng Y, Yan F, Chen J and Liu Y*, An efficient Potato virus X-based microRNA silencing in Nicotiana benthamiana, Scientific Reports 6: 20573, 2016

4.     Wang Y, Zheng X, Yu B, Han S, Guo J, Tang H, Deng H, Hong Y and Liu Y*, Disruption of microtubules in plants suppresses macroautophagy and triggers starchy chloroplast autophagy, Autophagy 11(12): 2259-74, 2015

5.     Han S,Wang Y, Zheng X, Jia Q, Zhao J, Bai F,Hong Y and Liu Y*, Cytoplastic glyceraldehyde-3-phosphate dehydrogenases interact with ATG3 to negatively regulate autophagy and immunity in Nicotiana benthamiana, Plant Cell  27(4):1316-31, 2015

6.     Yin K, Han T, Liu G. Chen T, Wang Y, Yu A and Liu Y*, A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing, Scientific Reports 5:14926, 2015

7.     Sha A, Zhao J, Yin K, Tang Y, Wang Y, Wei X, Hong Y, Liu Y*, Virus-based microRNA silencing in plants, Plant Physiology, 164(1):36-47, 2014.

8.     Du Y, Zhao J, Chen T, Liu Q, Zhang H, Wang Y, Hong Y, Xiao F, Zhang L, Shen Q and Liu Y*, Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity, PLoS Pathogens, 9(10): e1003659, 2013.

9.     Wang Y & Liu Y*,Autophagic degradation of leaf starch in plants, Autophagy, 9(8): 1247-1248, 2013

10.   Wang Y, Yu B, Zhao J, Guo J, Li Y, Han S, Huang L, Du Y, Hong Y, Tang D, and Liu Y*,Autophagy Contributes to the Leaf Starch Degradation, Plant Cell, 25(4): 1383-1399, 2013

11.   Zhang H, Zhao J, Liu S, Zhang D and Liu Y*, Tm-22 confers different resistance responses against Tobacco mosaic virus dependent on its expression level, Molecular Plant, 6(3): 971-974, 2013

12.   Zhao J, Liu Q, Zhang H, Jia Q, Hong Y, Liu Y*, The RuBisCO small subunit is involved in the tobamovirus movement and Tm-22-mediated extreme resistance, Plant Physiology,161(1): 374-83,2013

13.   Xu G, Li S, Xie K, Zhang Q, Wang Y, Tang Y, Liu D, Hong Y, He C, Liu Y*, Plant ERD2-like proteins function as ER luminal protein receptors and participate in programmed cell death during innate immunity, Plant Journal, 72(1): 57-69, 2012

14.   Cai J, Xie K, Lin L, Qin B, Chen B, Meng J, Liu Y*, Cotton leaf curl Multan virus newly reported to be associated with cotton leaf curl disease in China. Plant Pathology, 59:794-795,2010

15.   Tang Y, Wang F, Zhao J, Xie K, Hong Y, Liu Y*, Virus-based microRNA expression for gene functional analysis in plants, Plant Physiology 153 (2): 632-641, 2010

16.   Xu G, Sui N, Tang Y, Xie K, Lai Y, Liu Y*, One-step, zero-background ligation independent cloning intron-containing hairpin RNA constructs for RNAi in plants, New Phytologist 187 (1):240–250, 2010

17.   Burch-Smith T#, Schiff M#, Liu Y#, and Dinesh-Kumar SP, Efficient virus induced gene silencing in Arabidopsis thaliana, Plant Physiology, 142(1):21-27, 2006 (#co-first author)

18.   Liu Y, Schiff M, Czymmek K, Talloczy Z., Levine B and Dinesh-kumar SP. Autophagy regulates programmed cell death during the plant innate immune response, Cell, 121(4), 567-577, 2005

19.   Liu Y#, Burch-Smith T#, Schiff M, Feng S, Dinesh-Kumar SP. Molecular chaperone hsp90 associates with resistance protein n and its signaling proteins sgt1 and rar1 to modulate an innate immune response in plants. Journal of Biological Chemistry, 279(3): 2101-8, 2004 (#co-first author)

20.   Liu Y, Schiff M, Dinesh-Kumar SP, Functional requirement of A MAPK cascades, WRKY/MYB1 transcription factors, COI1 and CTR1 in N-mediated resistance to Tobacco mosaic virus, Plant Journal, 38(5), 800-809, 2004

21.   Liu Y#, Nakayama N#, Schiff M, Litt A, Irish VF and Dinesh-Kumar SP, Virus-induced silencing of a DEFICIENS ortholog in Nicotiana benthamiana, Plant Molecular Biology, 54(5), 701-711, 2004 (#co-first author)

22.   Bilgin D#, Liu Y#, Schiff M, Dinesh-Kumar S. P, P58IPK, a plant ortholog of double-stranded RNA-dependent protein kinase PKR inhibitor, functions in viral pathogenesis. Developmental Cell, 4, 651-661, 2003 (# co-first author)

23.   Xie Y, Liu Y*, Meng M, Chen L and Zhu Z*, Isolation and identification of a super strong plant promoter from Cotton leaf curl Multan virus, Plant Molecular Biology, 53(1), 1-14, 2003

24.   Liu Y, Schiff M, Dinesh-Kumar S. P. Virus-induced gene silencing in Tomato, Plant Journal 31(6), 777-786, 2002

25.   Liu Y, Schiff M, Serino G, Deng X-W and Dinesh-Kumar S. P, Role of SCF ubiqutin-ligase and the COP9 signalosome in the N-mediated resistance to tobacco mosaic virus, Plant Cell 14(7), 1483-1496, 2002

26.   Liu Y, Schiff M, Marathe R. and Dinesh-kumar. Tobacco Rar1, EDS1 and NPR1/NIM1 like genes are required for N-mediated resistance to tobacco mosaic virus. Plant Journal 30(4): 415-29, 2002

27.   Liu Y, Robinson DJ, Harrison BD, Defective forms of cotton leaf curl virus DNA-A that have different combinations of sequence deletion, duplication, inversion and rearrangement, Journal of General Virology, 79:1501-8, 1998

For more information, see

http://www.researcherid.com/rid/E-5700-2010

https://scholar.google.com/citations?user=bPE4qTYAAAAJ&hl=en&oi=ao

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E-mail:yuleliu@mail.tsinghua.edu.cn

 
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