Overview

Achievements

International cooperation

Key laboratory

 

Achievements

Publication in recent years

1, Yin P, Li QX, Yan CY, Liu Y, Liu JJ, Yu F, Wang Z, Long JF, He JH, Wang HW, Wang JW, Zhu JK, Shi YG, Yan NE. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature , 2013úČ504ú║168-71

2, Wang TL, Fu GB, Pan XJ, Wu JP, Gong XQ, Wang JW, Shi YG. Structure of a bacterial energy-coupling factor transporter. Nature, 2013,497: 272-6.

3, Li XC, Dang SY, Yan CY, Gong XQ, Wang JW, Shi YG. Structure of a presenilin family intramembrane aspartate protease. Nature, 2013, 493: 56-61.

4, Hu ZH, Yan CY, Liu PY, Huang ZW, Ma R, Zhang CL, Wang RY, Zhang YT, Martinon F, Miao D, Deng HT, Wang JW, Chang JB, Chai JJ. Crystal structure of NLRC4 reveals its autoinhibition mechanism. Science, 2013,341: 172-5.

5, Sun YD, Li L, Macho AP, Han ZF, Hu ZH, Zipfel C, Zhou JM, Chai JJ .Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex. Science, 2013, 342: 624-8.

6, Hu P, Zhou W, Cheng ZW, Fan M, Wang L, Xie DX. JAV1 Controls Jasmonate-Regulated Plant Defense. Molecular cell, 2013, 50: 504-15.

7, Zuo W, Huang F, Chiang YJ, Li M, Du J, Ding Y, Zhang T, Lee HW, Jeong LS, Chen YL, Deng HT, Feng XH, Luo SW, Gao CJ, Chen YG. c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor. Molecular cell, 2013, 49: 499-510.

8úČLi XL, Zhuo W, Yu J, Ge JP, Gu JK, Feng Y, Yang MJ, Wang LF, Wang N. Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain. Acta Crystallographica Section D: Biological Crystallography, 2013, 69: 256-65.

9, Wang DL, Huang BL, Zhang SY, Yu XJ, Wu W, Wang XQ. Structural basis for R-spondin recognition by LGR4/5/6 receptors. Genes & development, 2013, 27: 1339-44.

10, Wu YY, Wang X, Guo HJ, Zhang B, Zhang XB, Shi ZJ, Yu L. Synthesis and screening of 3-MA derivatives for autophagy inhibitors. Autophagy, 2013, 9: 595-603.

11, Zhang X, Xia MD, Li Y, Liu HH, Jiang X, Ren WL, Wu JP, DeCaen P, Yu F, Huang S, He JH, Clapham DE, Yan N, Gong HP. Analysis of the selectivity filter of the voltage-gated sodium channel NavRh. Cell research, 2013, 23: 409-22.

12, Wang NS, Shi XL, Jiang LW, Zhang SY, Wang DL, Tong P, Guo DX, Fu LL, Cui Y, Liu X, Arledge KC, Chen YH, Zhang LQ, Wang XQ. Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4. Cell research, 2013, 23: 986-93.

13, Liu XF, Xiong C, Jia SJ, Zhang Y, Chen YG, Wang Q, Meng AM. Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region. Nature communications, 2013, 4: 1728.

14, Cao MQ, Meng D, Wang L, Bei SQ, Snell WJ, Pan JM. Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length. Proceedings of the National Academy of Sciences, 2013, 110: 12337-42.

15, Xiao GR, Fan QW, Wang XX, Zhou B. Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding. Proceedings of the National Academy of Sciences, 2013, 110: 14995-15000.     

16, Wang Y, Yu BJ, Zhao JP, Guo JB, Li Y, Han SJ, Huang L, Du YM, Hong YG, Tang DZ, Liu YL. Autophagy contributes to leaf starch degradation. The Plant Cell Online, 2013, 25: 1383-99.

17, Yan JB, Li HO, Li SH, Yao RF, Deng HT, Xie Q, Xie DX. The Arabidopsis F-box protein CORONATINE INSENSITIVE1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway. The Plant Cell Online, 2013, 25: 486-498.

   
Tsinghua University,Beijing,China,100084
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