Full time faculty

Adjunct professor

Chair professor


Fanglin Sun


Fanglin Sun

Ph.D. Professor
Dr. Sun was born at Shan Dong province in 1968. From 1993, he studied "Genomic Imprinting and Epigenetics" at The Baraham Institute, Cambridge, UK and obtained his Ph. D from University of Cambridge in 1997. He then joined in the Department of Biology, Washington University (St. Louis) as a Keck postdoctoral fellow and postdoctoral research associate, where he studied the mechanism of epigenetic gene silencing in heterochromatin. From 2001, he became a group leader at the Friedrich Meisher Institute for Biomedical Research, Switzerland, where his group continued to investigate the function and mechanism of epigenetic regulation in development. He returned to China in June, 2006 and became Professor at the School of Medicine, Tsinghua University. He was awarded "National Jie-Qing Scholarship" from the Chinese National Science Foundation (CNSF) in 2006. He then became the "Chang-Jiang Scholar" Professor (Epigenetics) of the Chinese Ministry of Education at 2007. Currently, he is the Assistant Dean of the School of Medicine, Tsinghua University. He is also a member of the Academic Committee, Tsinghua University and member of the Steering Committee for the "Epigenetics Research Program" of the CNSF etc.
His group at the Tsinghua University is mainly interested in: 1) The mechanism and function of epigenetic regulation in stem cell differentiation and development, 2) The pathways of epigenetic regulation in cancer.
Dr. Sun and his group made a number of progresses on understanding the role and mechanism of gene silencing in heterochromatin, the function of epigenetic regulators in development. They have published a number of papers on the top journals, such as Nature, Cell, Nature Genetics, Genes & Development and PNAS etc.


Selected Publications
•Sun F.L., Dean W.L., Kelsey G., Allen N. D. and Reik W. (1997). Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome. Nature (full article), 389: 809 – 815.
•Sun F.L and Elgin S.C.R. (1999). Putting boundaries on silence. Cell, 99: 459-6
•Sun F.L. Cuaycong M.H. Craig C. A. Wallrath L.L. Locke J. and Elgin S.C.R. (2000). The fourth chromosome of Drosophila melanogaster: interspersed euchromatic and heterochromatic domains. Proc Natl Acad Sci U S A. 97: 5340-45.
•Sun F.L. Cuaycong M.H. and Elgin S.C.R. (2001). Long-range nucleosome ordering is associated with gene silencing in Drosophila melanogaster pericentric heterochromatin. Mol. Cell. Biol. 21: 2867-79.
•Sun FL, Haynes K, Simpson CL, Lee SD, Collins L, Wuller J, Eissenberg JC, Elgin SC (2004). cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four. Mol Cell Biol. 24:8210-20.
•De Lucia F, Ni JQ, Vaillant C, Sun F-L.** (2005). HP1 modulates the transcription of cell-cycle regulators in Drosophila melanogaster. Nucleic Acids Res. 33: 2852-58.
•Liu L.-P., Ni J.-Q., Shi Y-D, Oakeley, E. and Sun F-L** (2005). Sex-specific role of Drosophila HP1 in chromatin and transcription. Nature Genetics 37: 1361-66
•Ni, J-Q, Liu L-P, Hess D., Rietdorf J.,1 and Sun F-L** (2006). Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription. Genes & Development 20: 1959-73
** corresponding author
Tel: 010-62792720/62784371


Tsinghua University,Beijing,China,100084
Tel:+86-10-62772269  Fax:+86-10-62788604  Email:swxrs@tsinghua.edu.cn