Full time faculty

Adjunct professor

Chair professor


KehKooi Kee


KehKooi Kee, PhD


1992-1997       Iowa State University, USA  (Biochemistry)
                           Bachelor of Science & Master of Science
1997-2003       Weill Cornell Medical College/ Memorial Sloan Kettering Cancer Center, USA (Molecular, Cellular Biology & Genetics)
2004-2007       UCSF, USA Postdoctoral Fellow
2007-2010       Stanford University, USA Research Associate
May 2010-        Tsinghua University, China, Professor

Research interest:

  1. Human stem cell and germ cell biology: Using in vitro differentiation of human stem cells to study molecular and genetic mechanisms of germ cell development, from stem cells to mature sperms and oocytes.
  2. Human genetic diseases: Combining iPS and site specific mutagenesis to develop treatment for genetic diseases.


  1. Kehkooi Kee, Renee Reijo Pera, Paul Turek. Testicular Germline Stem Cell. Nature Review of Urology. 2010 Feb;7(2):94-100. [Epub 2010 Jan 19].
  2. Kehkooi Kee, Vanessa Angeles, Marty Flores, Ha Nam Nguyen & Renee Reijo Pera. DAZL, DAZ, and BOULE modulate human primordial germ cell and haploid gamete formation. Nature. 2009 Nov 12; 462(7270):222-5. [Epub 2009 Oct 28].
  3. International Stem Cell Initiative members. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nature Biotechnol. 2007 Jul; 25(7):803-16.
  4. Kehkooi Kee, Joanna Gonsalves, and Renee Reijo Pera. Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells. Stem cell and Development. 2006 Dec; 15(6):831-37.
  5. Kiersten A. Henderson, Kehkooi Kee, Shohreh Maleki, Paul Santini, and Scott Keeney. Cyclin-dependent kinase directly regulates initiation of meiotic recombination. Cell. 2006 Jun 30; 125(7):1321-32.
  6. Kehkooi Kee, Reine U. Protacio, Charanjit Arora and Scott Keeney. Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J. 2004 Apr 21;23(8):1815-24. [Epub :2004 Mar 25].
  7. Charanjit Arora, Kehkooi Kee, Shohreh Maleki, and Scott Keeney. Antiviral protein Ski8 is a direct partner of Spo11 in meiotic double-strand break formation, independent of its cytoplasmic role in RNA metabolism. Molecular Cell, 2004 Feb 27;13(4):549-59.
  8. Kehkooi Kee and Scott Keeney. Functional Interactions Between SPO11 and REC102 During Initiation of Meiotic Recombination in Saccharomyces cerevisiae. Genetics. 2002 Jan;160(1):111-22.
  9. Kehkooi Kee, Luming Niu, and Eric Henderson. A Tetrahymena thermophila G4-DNA binding protein with dihydrolipoamide dehydrogenase activity. Biochemistry. 1998 Mar 24;37(12):4224-34.

Contact info:

Tel:+86-10-62794200(office) , 62785820 (lab)
Email: kkee@mail.tsinghua.edu.cn

Tsinghua University,Beijing,China,100084
Tel:+86-10-62772269  Fax:+86-10-62788604  Email:swxrs@tsinghua.edu.cn