Full time faculty

Adjunct professor

Chair professor


Haipeng Gong

Haipeng Gong, Ph.D.
Principal Investigator
Professional Experience
2015-present, Tenured associate professor, School of Life Sciences, Tsinghua University
2009-2014, Tenure-track assistant professor, School of Life Sciences, Tsinghua University
2007-2009, Postdoc, Department of Biochemistry and Molecular Biology, University of Chicago
2006-2007, Postdoc, Program of Molecular Biophysics, Johns Hopkins University
2000-2006, Ph.D., Program of Molecular Biophysics, Johns Hopkins University 
1997-2000, M.S., Department of Biological Science and Biotechnology, Tsinghua University
1993-1997, B.S., Department of Biological Science and Biotechnology, Tsinghua University
Research Interest
1. Studying the dynamics and interaction mechanism of macromolecules by molecular dynamics (MD) simulation.
2. Predicting the tertiary structures of proteins from their primary sequences.
Selected Publication
1. Ruining Sun# and Haipeng Gong*, “Simulating the activation of voltage sensing domain for a voltage-gated sodium channel using polarizable force field”, Journal of Physical Chemistry Letters, 8: 901-908, 2017
2. Yang Li#, Ruining Sun#, Huihui Liu, and Haipeng Gong*, “Molecular dynamics study of ion transport through an open model of voltage-gated sodium channel”, Biochimica et Biophysica Acta – Biomembranes, 1859(5): 879-887, 2017.
3. Xiaoying Lv#, Hao Liu, Haifeng Chen, and Haipeng Gong*, “Coupling between ATP hydrolysis and protein conformational change in maltose transporter”, Proteins: Structure, Function and Bioinformatics, 85(2): 207-220, 2017.
4. Tong Wang#, Yuedong Yang, Yaoqi Zhou, and Haipeng Gong*, “LRFragLib: an effective algorithm to identify fragments for de novo protein structure prediction”, Bioinformatics, 33(5): 677-684, 2017.
5. Yang Li#, Huihui Liu#, Mengdie Xia, and Haipeng Gong*, “Lysine and the Na+/K+ selectivity in mammalian voltage-gated sodium channels”, PLoS One, 11(9): e0162413, 2016.
6. Huihui Liu#, Yan-Song Gao#, Xiang-Jun Chen, Zhe Chen, Hai-Meng Zhou, Yong-Bin Yan*, and Haipeng Gong*, “A single residue substitution accounts for the significant difference in thermostability between two isoforms of human cytosolic creatine kinase”, Scientific Reports, 6: 21191, 2016.
7. Yufeng Liu#, Meng Ke, and Haipeng Gong*, “Protonation of Glu135 facilitates the outward-to-inward structural transition of fucose transporter”, Biophysical Journal, 109(3): 542-551, 2015.
8. Dapeng Xiong#, Jianyang Zeng, and Haipeng Gong*, “RBRIdent: an algorithm for improved identification of RNA-binding residues in proteins from primary sequences”, Proteins: Structure, Function and Bioinformatics, 83(6):1068-1077, 2015.
9. Juanrong Zhang#, Wenzhi Mao#, Yanhui Ren#, Rui-Ning Sun, Nieng Yan*, and Haipeng Gong*, “Simulating the ion permeation and ion selection for a eukaryotic voltage-gated sodium channel NavPaS”, Protein & Cell, in press, 2018.
10. Meng Ke#, Yafei Yuan, Xin Jiang, Nieng Yan*, and Haipeng Gong*, “Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE”, PLoS Computational Biology, 13(6): e1005603, 2017.
11. Dapeng Xiong#, Jianyang Zeng*, and Haipeng Gong*, “A deep learning framework for improving long-range residue-residue contact prediction using a hierarchical strategy”, Bioinformatics, 33(17): 2675-2683, 2017.


Contact Information
Office: #C308, Medical Science Building, Tsinghua University
Tel: 010-62794753 (office), 010-62794737(lab)
Email: hgong@tsinghua.edu.cn

Tsinghua University,Beijing,China,100084
Tel:+86-10-62788604  Fax:+86-10-62788604  Email:admin-life@biomed.tsinghua.edu.cn