Full time faculty

Adjunct professor

Chair professor

Administration

Zhen Li

 

Zhen LI, Professor

Education:
B.S., Wuhan University, PRC, 1988,
Ph.D., Carnegie-Mellon University, USA, 1995
 
Research Experience:
Post-doctoral fellow, University of Michigan, USA, 1995-1997
Post-doctoral fellow, Stanford University, USA, 1997-1999
Research associate, Hong Kong University of Science and Technology, Hong Kong, PRC, 2000-2003
Associate professor, Tsinghua University, PRC, 2004-present
 
Main research fields:
1. Molecular mechanism of adiponectin multimerization and secretion
2. Identification of new drugs for the treatment of Type 2 diabetes
 
Course tought:
Biochemistry I (English)
Biochemistry II (English)
 
Publications:
  • Liu LH, Xie JY, Guo WW, Wu GY, Chen ZF, Yi JY, Zhang L, Zhang ZJ, Li Z. 2014. Evodiamine activates AMPK and promotes adiponectin multimerization in 3T3-L1 adipocytes. J Asian Nat Prod Res. Aug 1:1-10. [Epub ahead of print]
  • Wu G, Yi J, Liu L, Wang P, Zhang Z, Li Z. 2013. Pseudoginsenoside F11, a Novel Partial PPARγ Agonist, Promotes Adiponectin Oligomerization and Secretion in 3T3-L1 Adipocytes. PPAR Res. Epub 2013 Dec 18.
  • Chen Z, Zhang L, Yi J, Yang Z, Zhang Z, Li Z. 2012. Promotion of adiponectin multimerization by emodin, a novel AMPK activator with PPARg-agonist activity. J Cell Biochem. 113(11):3547-58.
  • Lin H, Li Y, Li Y, Yi J, Mai Y, Li Z. 2012. Tanshinone IIA promotes the assembly of adiponectin in 3T3-L1 adipocytes. Chin J of Nat Med. 10(2):150-154.
  • Lin H, Li Z. 2012. Adiponectin self-regulates its expression and multimerization in adipose tissue: an autocrine/paracrine mechanism? Med Hypotheses. 78(1):75-8.
  • Li Y, Wang P, Zhuang Y, Lin H, Li Y, Liu L, Meng Q, Cui T, Liu J, Li Z. 2011. Activation of AMPK by berberine promotes adiponectin multimerization in 3T3-L1 adipocytes. FEBS Lett. 585(12):1735-40.
  • Li Z, David GHung K-W, DePinho R A, Fu A K Y, and Ip N Y. 2004.
  • Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription. J Biol Chem. 279: 54438-54444.
  • Cheng K*, Li Z*, Fu W-Y, Wang J H, Fu A K Y, and Ip N Y. 2002. Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35. J Biol Chem. 277: 31988-31993.
 Honors
Member of the Program for New Century Excellent Talent in Universities (NCET), Ministry of Education, PRC, 2004-2007 
                                                       
Contact:
School of Life Sciences,
Tsinghua University
Tel & Fax: (86)-10-62770581
Email:lizhen@tsinghua.edu.cn
 
 


Tsinghua University,Beijing,China,100084
Tel:+86-10-62788604  Fax:+86-10-62788604  Email:admin-life@biomed.tsinghua.edu.cn