Full time faculty

Adjunct professor

Chair professor

Administration

Zhen Li

 

Zhen LI, Professor

1988             Wuhan University                             B.S.

1995             Carnegie-Mellon University, USA                  Ph.D.

1995-1997    University of Michigan, USA               Postdoctor

1997-1999  Stanford University, USA                  Postdoctor

2000-2003    HKUST, Hong Kong                          Research Associate

2004-Present School of Life Sciences, Tsinghua University       Associate Professor, Professor

 

Main Courses And Research Fields

Molecular mechanism of adiponectin

multimerization and secretion

Adiponectin-targeted drug development for Type 2 diabetes

 

Selected Publications

1.Wang Y, Zhang Y, Wang Y, Peng H, Rui J, Zhang Z, Wang S, Li Z. 2017.WSF-P-1, a novel AMPK activator, promotes adiponectin multimerization in 3T3-L1 adipocytes. Biosci Biotechnol Biochem. 81(8):1529-1535

2.Liu LH, Xie JY, Guo WW, Wu GY, Chen ZF, Yi JY, Zhang L, Zhang ZJ, Li Z.2014. Evodiamine activates AMPK and promotes adiponectin multimerization in 3T3-L1 adipocytes. J Asian Nat Prod Res. 16(11):1074-83.

3.Wu G, Yi J, Liu L, Wang P, Zhang Z, Li Z. 2013. Pseudoginsenoside F11, a Novel Partial PPARγ Agonist, Promotes Adiponectin Oligomerization and Secretion in 3T3-L1 Adipocytes. PPAR Res. Epub 2013 Dec 18.

4.Chen Z, Zhang L, Yi J, Yang Z, Zhang Z, Li Z. 2012. Promotion of adiponectin multimerization by emodin, a novel AMPK activator with PPARγ-agonist activity. J Cell Biochem. 113(11):3547-58.

5.Lin H, Li Y, Li Y, Yi J, Mai Y, Li Z. 2012. Tanshinone IIA promotes the assembly of adiponectin in 3T3-L1 adipocytes. Chin J of Nat Med. 10(2):150-154.

6.Lin H, Li Z. 2012. Adiponectin self-regulates its expression and multimerization in adipose tissue: an autocrine/paracrine mechanism? Med Hypotheses. 78(1):75-8.

7.Li Y, Wang P, Zhuang Y, Lin H, Li Y, Liu L, Meng Q, Cui T, Liu J, Li Z. 2011. Activation of AMPK by berberine promotes adiponectin multimerization in 3T3-L1 adipocytes. FEBS Lett. 585(12):1735-40.

 

Contact

TEL/FAX£º+86-10-62770581

E-mail:lizhen@mail.tsinghua.edu.cn

 



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