Full time faculty

Adjunct professor

Chair professor

Administration

Jianlin Lei

Lei, Jianlin, Ph.D

Education
1998     Ph. D. in Condensed Matter Physics, Wuhan University, China
1993     B.S. in Physics, Wuhan University, China

Research Experience
2008-present          Professor, School of Life Sciences, Tsinghua University
2008                      Associate Research Scientist, Department of Biochemistry and Molecular Biophysics, Columbia University
2000-2008              Research Affiliate, Wadsworth Center, New York State Department of Health
1999-2000              Visiting Scholar, Institute of Crystallography, Ludwig-Maximilians-Universität München
1998-2000              Postdoctoral Fellow, Beijing Laboratory of Electron Microscopy, Institute of Physics, Chinese Academy of Sciences

Research Interests:
High-throughput automated electron microscopy for three-dimensional reconstruction.
Studies on the structure and function of macromolecular complexes using cryo-electron microscopy.

Selected Publications

  1. Agirrezabala, X., Lei, J., Brunelle, J., Ortiz-Meoz, R., Green, R., and Frank, J. (2008). Visualization of the Hybrid State of tRNA Binding Promoted by Spontaneous Ratcheting of the Ribosome. Molecular Cell 32, 190–197.
  2. Li, W., Agirrezabala, X., Lei, J., Bouakaz, L., Brunelle, L., Ortiz-Meoz, R., Green, R., Sanyal, S., Ehrenberg, M. and Frank, J. (2008). Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. The EMBO Journal 27, 3322-3331.
  3. Lei, J., and Frank, J. (2005). Automated acquisition of cryo-electron micrographs for Single particle reconstruction on an FEI Tecnai electron microscope. Journal of Structural Biology 150, 69–80.
  4. Weidner, E., Frey, F., Lei, J., Pedersen, B., Paulmann, C., and Morgenroth, W. (2004). Disordered quasicrystals: diffuse scattering in decagonal Al-Ni-Fe. J. Appl. Cryst. 37, 802-807
  5. Weidner, E., Lei, J., Frey, F., Wang, R., and Grushko, B. (2002). Diffuse scattering in decagonal Al–Ni–Fe. Journal of Alloys and Compounds 342, 156-158.
  6. Lei, J., Wang, R., Yin, J., and Duan, X. (2002). Diffuse electron scattering determination of elastic constants of Al–Pd–Mn icosahedral quasicrystal. Journal of Alloys and Compounds 342, 326-329.
  7. Wang, R., Hu, C., Lei, J. (2001). Theory of diffuse scattering of quasicrystals due to fluctuations of thermalised phonons and phasons. Phys. Stat. Sol. (b) 225, 21-34.
  8. Lei, J., Wang, R., Hu, C., and Ding, D. (2000). Diffuse scattering from dodecagonal quasicrystals. Eur. Phys. J. B 13, 21-30.
  9. Wang, R., Hu, C., Lei, J., and Ding, D. (2000). Theoretical aspects of thermal diffuse scattering from quasicrystals. Phys. Rev. B 61, 5843-5845.
  10. Lei, J., Wang, R., Hu, C., and Ding, D., (1999). Diffuse scattering from decagonal quasicrystals. Phys. Rev. B 59, 822-828.
  11. Lei, J., Hu, C., Wang, R., and Ding, D., (1999). Diffuse scattering from octagonal quasicrystals. J. Phys.: Condens. Matter 11, 1211-1223.
  12. Lei, J., Wang, R., Hu, C., and Ding, D. (1998). Diffuse scattering from pentagonal quasicrystals. Phys. Lett. A 247, 343-352.
  13. Wang, J., Lei, J., and Wang, R. (1998). Diffraction pattern calculation and phase identification of hypothetical crystalline C3N4. Phys. Rev. B 58, 11890-11895.

Contacts:
Tel: +86-10-62797699
Fax: +86-10-62784259
E-mail: jllei at tsinghua.edu.cn (Please replace at by@)



Tsinghua University,Beijing,China,100084
Tel:+86-10-62772269  Fax:+86-10-62788604  Email:swxrs@tsinghua.edu.cn