Full time faculty

Adjunct professor

Chair professor


Zhirong Sun

Zhirong Sun
Professor of Bioinformatics, Ph.D. Advisor

1970£¬BS.  Tsinghua University;
1970—1984, Teacher in the Automation Department of Tsinghua University;

Research Experience:
1984—2009, full professor,School of Life Sciences, Tsinghua University.
1992-1993, Visiting Scientist at Birkbeck College;
1997-1998, Visiting Scientist in UIUC;
2002, Visit to UCSD.
2004, Visit to UGA.
2007, Visit to SFU.
2008, Visit to MIT for iGEM.

Main Research Fields: 
Genomics¡¢Proteomics and Bioinformatics¡¢system biology.

Current research interests:
·Theoretical and experimental research on combinational transcriptional regulation.
·Topology analysis and dynamic modeling of molecular network and pathway.
·Study on identifying molecular markers of some common cancers (eg. lung cancer) and uncovering mechanism of tumor genesis on “pathway” level.

“Biophysics”(undergraduate of dept.of biology, Tsinghua) (with Prof. Sui SF),1994—2009.
“Structure and function of Bio-macromoleculae”, (graduate of Tsinghua), 1994—1999.
“Bioinformatics”(graduate of Tsinghua), 1999—2009.

Selected  Publications
1) Hua SJ & Sun ZR*. (2001). A Novel Method of Protein Secondary Structure Prediction with High Segment Overlap Measure: Support Vector Machine Approach. J.Mol.Biol., 308:397-407.
2) Hua SJ & Sun ZR*. (2001). Support Vector Machine Approach for Protein Subcellular Localization Prediction. Bioinformatics., 17:721-728.
3) Hua SJ, Guo T, Gough J & Sun ZR*. (2002). Proteins with Class Alpha/Beta Fold Have High-level Participation in Fusion Events.  J. Mol. Biol.., 320:713-719
4) Zheng JS, Wu JJ, and Sun ZR* An Approach to Identify Over-represented Cis-elements in Related Sequences. Nucleic Acids Research. 2003, V31, N7, 1-11.
5) Ji XL, Y Y, Li L, Li YD & Sun ZR*£¬  HMMGEP: clustering gene expression data using hidden Markov models.   Bioinformatics. 2004. Feb 26
6£©Zi Z, Cho KH, Sung MH, Xia X, Zheng J, Sun Z.R*., In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway. FEBS Lett. 2005 Feb 14;579(5):1101-8.
7£©Zhou Y1,Wang R2,Li L1,Xia Xf1 & Sun ZR 1* Inferring functional linkages between proteins from evolutionary scenarios 2006. J.Mol.Biol. 359(4):1150-9.
8£©Chen H1†, Xue Y 2†, Huang N1, Yao Xb 2* and Sun ZR1*.  MeMo: A web tool for prediction of   
  protein methylation modifications. 2006. Nucleic Acids Research. 2006 Jul 1;34:W249-53.
9) Hu Chen, Ni Huang and Zhirong Sun*, SubLoc: A Server/Client Suite for Protein Subcellular Location based on SOAP. Bioinformatics.  2006 Feb 1;22(3):376-7.
10) Li Li, Yingwu Huang, Xuefeng Xia, Zhirong Sun*,  Preferential Duplication in the Sparse Part of Yeast Protein Interaction Network. Mol Biol Evol. 2006. 23(12):2467-73.
11) Sun Z*,Luo J,Zhou Y,Luo J,Liu K and Li W. Exploring phenotype -associated modules in an oral cavity tumor using an integrated framework. Bioinformatics. 2009 Jan 29. 25(6):795-800.

phone: 010-62772237


E-mail: sunzhr@mail.tsinghua.edu.cn£©



Tsinghua University,Beijing,China,100084
Tel:+86-10-62772269  Fax:+86-10-62788604  Email:swxrs@tsinghua.edu.cn