Full time faculty

Adjunct professor

Chair professor

Administration

Qiong Wu

Wu Qiong, Ph.D.

Principal Investigator

 

Education

1991-1996   B.S, Tsinghua University

1996-2001   Ph.D, Tsinghua University

 

Work Experience

Lecturer, School of Life Sciences, Tsinghua University (2001)

Associate professor, School of Life Sciences, Tsinghua University (2006)

PhD advisor, School of Life Sciences, Tsinghua University (2010)

 

Research Focus

1.        Understanding the regulatory network in cartilage regeneration process through single cell analysis.

2.        Understanding noncoding RNA participated cell-cell communication in blood vessel regeneration.

3.        Precise control of tissue engineering seeding cell biological regulation using synthetic engineering approach.

4.        Developing functional biomaterials for tissue engineering based on PHA, and exploring novel approaches for evaluation of implantation outcomes.

Our group is currently focusing on understanding the both coding gene and noncoding RNA regulatory mechanism of cartilage and blood vessel regeneration. We are trying to precisely regulate the seeding cell behavior to meet the tissue engineering demands using synthetic biology concept, and developing novel functional biomaterials for an improved therapeutic outcomes.

 

Teaching

Genetic Experiments for undergraduate students

 

Representative Publications

1.        Yao, Y., S. Jin, H. Long, Y. Yu, Z. Zhang, G. Cheng, C. Xu, Y. Ding, Q. Guan, N. Li, S. Fu, X. J. Chen, Y. B. Yan, H. Zhang, P. Tong, Y. Tan, Y. Yu, S. Fu, J. Li, G. J. He, and Q. Wu*, 2015, RNAe: an effective method for targeted protein translation enhancement by artificial non-coding RNA with SINEB2 repeat: Nucleic Acids Res, in press.

2.        Li, J., Y. Ma, R. Teng, Q. Guan, J. Lang, J. Fang, H. Long, G. Tian, and Q. Wu*, 2015, Transcriptional profiling reveals crosstalk between mesenchymal stem cells and endothelial cells promoting prevascularization by reciprocal mechanisms: Stem Cells Dev, v. 24, p. 610-23.

3.        Yao Y., He Y., Guan Q., Wu Q.*, A tetracycline expression system in combination with Sox9 for cartilage tissue engineering. Biomaterials, 2014, 35: 1898-1906.

4.        Lin X., Wu L., Zhang Z.M., Yang R.H., Guan Q., Hou X.F., Wu Q.*, MiR-335-5p Promotes Chondrogenesis in Mouse Mesenchymal Stem Cells and is Regulated Through Two Positive Feedback Loops. Journal of Bone and Mineral Research. in press

5.        Wang Y., Jiang X.L., Yang S.C., Lin X., He Y., Yan C., Wu L., Chen G.Q., Wang Z.Y., Wu Q.*, MicroRNAs in the regulation of interfacial behaviors of MSCs cultured on microgrooved surface pattern. Biomaterials, 2011, 32: 9207-9217.

6.        Yan C., Wang Y., Shen X.Y., Yang G., Jian J., Wang H.S., Chen G.Q., Wu Q.*, MicroRNA regulation associated chondrogenesis of mouse MSCs grown on polyhydroxyalkanoates. Biomaterials, 2011, 32: 6435-6444.

7.        Bian Y.Z., Wang Y., Aibaidula G., Chen G.Q., Wu Q.*, Evaluation of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Conduits for Peripheral Nerve Regeneration, Biomaterials 2009, 30: 217–225

8.        Wang Y., Bian Y.Z., Wu Q.*, Chen G.Q.,* Evaluation of three-dimensional scaffolds prepared from poly(3-hydroxybutyrateco-3-hydroxyhexanoate) for growth of allogeneic chondrocytes for cartilage repair in rabbits Biomaterials, 2008, 29: 2858–2868

9.        Cheng S., Chen G.Q., Leski M., Zou B., Wang Y., Wu Q.*, The effect of D,L-β-Hydroxybutyric acid on cell death and proliferation in L929 cells Biomaterials 2006,27: 3758-3765

10.    Wang Y.W., Wu Q.*, Chen G.Q., Attachment, Proliferation and Differentiation of Osteoblasts on Random Biopolyester Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) Scaffolds. Biomaterials, 2004, 25: 669-675

 

Honors

2001    1st Class Award for Outstanding Scientific Achievement (by Beijing Government) (The Third Contributor)

2002      National Invention Silver Medal Award (Chinese Ministry of Sci and Technol) (The third Contributor)

2004    1st Class Award for Beijing Municipal education achievement (The Third Contributor)

2005     2st Class Award for National Teaching achievement (The Third Contributor)

2008     2st Class Award for Tsinghua University Teaching achievement (The Fourth Contributor)

2008     New Century Excellent Talent Scheme supported by Ministry of Education

2012     2st Class Award for Beijing Municipal Science and Technology Progress (The Second Contributor)

 

Contact

Tel: 010-62771664

Fax: 86-010-62794217

E-mail: wuqiong@mail.tsinghua.edu.cn



Tsinghua University,Beijing,China,100084
Tel:+86-10-62772269  Fax:+86-10-62788604  Email:swxrs@tsinghua.edu.cn