Full time faculty

Adjunct professor

Chair professor


Haimeng Zhou

Hai-Meng Zhou Ph.D
1970, B.S, Department of Chemical Engineering, Tsinghua University.
1981, M.S, Department of Chemical Engineering, Tsinghua University.
1986, Ph.D., Institute of Biophysics, Academia Sinica.

Dr. Zhou holds the following appointments concurrently: Professor of Tsinghua University; Director of the Laboratory of Molecular Enzymology.
Main Research Fields: Research of our laboratory is the structure-function analysis of enzymes, including chemical modification, catalytic kinetics and the effects of changes in structures on the catalytic activities of enzymes. Current research focuses on protein-protein interactions and regulation of enzyme molecules.

Selected Publications
•Chen Z, Li J, Li QS, Fan JQ, Dong XM, Xu JP, Wang XM, Yang GW, Yan P, Wen GZ, Zhang YT, Niu RG, et al. Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer. Oncogene 2008;27:3483-8.
•Qi J, Gong J, Zhao T, Zhao J, Lam P, Ye J, Li JZ, Wu J, Zhou HM, Li P. Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue. Embo J 2008;27:1537-48.
•Lu Y, Lu YS, Shuai Y, Feng C, Tully T, Xie Z, Zhong Y, Zhou HM. The AKAP Yu is required for olfactory long-term memory formation in Drosophila. Proc Natl Acad Sci U S A 2007;104:13792-7.
•Zhao TJ, Yan YB, Liu Y, Zhou HM. The generation of the oxidized form of creatine kinase is a negative regulation on muscle creatine kinase. J Biol Chem 2007;282:12022-9.
•Zhao TJ, Sun S, Liu Y, Liu JM, Liu Q, Yan YB, Zhou HM. Regulating the drought-responsive element (DRE)-mediated signaling pathway by synergic functions of trans-active and trans-inactive DRE binding factors in Brassica napus. J Biol Chem 2006;281:10752-9.
•Jiang Y, Yan YB, Zhou HM. Polyvinylpyrrolidone 40 assists the refolding of bovine carbonic anhydrase B by accelerating the refolding of the first molten globule intermediate. J Biol Chem 2006;281:9058-65.
•Zhao TJ, Ou WB, Xie Q, Liu Y, Yan YB, Zhou HM. Catalysis of creatine kinase refolding by protein disulfide isomerase involves disulfide cross-link and dimer to tetramer switch. J Biol Chem 2005;280:13470-6.


Tsinghua University,Beijing,China,100084
Tel:+86-10-62772269  Fax:+86-10-62788604  Email:swxrs@tsinghua.edu.cn