Full time faculty

Adjunct professor

Chair professor


Geng Wang

Geng Wang


Principal Investigator

Young 1000-Talent Plan


1994-1998:  B.S., Department of Chemistry, Xiamen University

1998-2000:  Department of Chemistry, Xiamen University

2000-2006:  Ph.D., Department of Biochemistry, University of Iowa

2006-2012:  Postdoctoral fellow, Department of Chemistry and Biochemistry, University of California, Los Angeles

2012-present: Principle Investigator, Tsinghua University School of Life Science

Main Research Fields:

1) Mitochondrial RNA import, metabolism, functions, and the regulation network between them and other important cellular processes such as aging and apoptosis.

2) Therapeutic research on mitochondrial diseases.

Selected Publications:


von Ameln S., G. Wang, R. Boulouiz, M.A. Rutherford, G.M. Smith, Y. Li, . Pogoda, G. Nürnberg, A.E. Volk, B. Stiller, R.J. Goodyear, P. Nürnberg, G.P. Richardson, M. Hammerschmidt, T. Moser, B. Wollnik, C.M. Koehler, M.A. Teitell, A. Barakat, C. Kubisch*. 2012.An indispensable role of the mitochondrial RNA-import protein PNPase for human auditory function. Am. J. Hum. Genet. 91(5):919.

Wang G., E. Shimada, J. Zhang, G.M. Smith, J.S. Hong, M.A. Teitell, C.M. Koehler*. 2012. A Novel Approach for Restoring the Functions of Mutant Mitochondria in Human Cells. Proc. Natl. Acad. Sci. U.S.A. 109(13):4840-5.

Wang G., E. Shimada, C.M. Koehler, and M.A. Teitell*. 2012. PNPASE and RNA Trafficking into Mitochondria. Biochim. Biophys. Acta. 1819(9-10):998-1007.

Zhang J., I. Khvorostov, J. Hong, Y. Oktay, L. Vergnes, E. Nuebel, P. Wahjudi, G. Wang, A. Do, H, Jung, J.M. McCaffery, I. Kurland, K. Reue, W.N.P. Lee, C.M. Koehler, M.A. Teitell*. 2011, UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 30(24):4860.

Wang G., H. Chen, Y. Oktay, J. Zhang, E.L. Allen, G.M. Smith, K.C. Fan, J.S. Hong, S.W. French, J.M. McCaffery, R.N. Lightowlers, H.C. Morse III, C.M. Koehler, and M.A. Teitell*. 2010. PNPASE Regulates RNA Import into Mitochondria. Cell 142:456.

Wang, G., R. Deschenes*, 2006. Plasma membrane localization of Ras requires Class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae. Mol. Cell. Biol. 26:3243.

Liu P, Huang J, Zheng Q, Xie L, Lu X, Jin J, Wang G (2017) Mammalian mitochondrial RNAs are degraded in the mitochondrial intermembrane space by RNASET2. Protein & Cell 8(1): 735-749

Wang G, Shimada E, Nili M, Koehler CM, Teitell MA (2015) Mitochondria-targeted RNA import. Methods Mol Biol. 1264:107-116



Tel: +86-010-62783944

E-mail: wangeng@hotmail.com

Tsinghua University,Beijing,China,100084
Tel:+86-10-62788604  Fax:+86-10-62788604  Email:admin-life@biomed.tsinghua.edu.cn