Full time faculty

Adjunct professor

Chair professor


Guanjun Gao

Guanjun Gao, Ph.D.
Principal Investigator
2000-2005  Ph.D.  Zhejiang University, China
1992-1996  B.S.   Yangzhou University, China
Research Position
2011-   Principal Investigator, School of Life Sciences, Tsinghua University
2010-2011  Research Fellow, National Cancer Institute, NIH, USA
2006-2010  Postdoctoral Fellow, National Cancer Institute, NIH, USA
Research Interests
Drosophila is one of the best genetic model organisms in the biomedical field. The main mission of our lab’s research is to achieve a comprehensive understanding of the mechanisms of epigenetic factors involved in reproductive system and embryonic development. 
Representative Publications
1. Wen K#, Yang L#, Xiong T#, Di C ,Ma D, Wu M, Xue Z, Zhang X, Long L, Zhang J, Bi X, Dai J, Zhang Ren M, Long L, Zhang Q, Lu ZJ.& Gao G*.Critical roles of long noncoding RNAs in Drosophila spermatogenesis. Genome Research. 2016 Sep;2 
2. Xiao X#, Yang L#, Pang X#, Zhang R, Zhu Y, Wang P, Gao G*& Cheng G*. A Mesh-Duox pathway regulates homeostasis in the insect gut. Nature Microbiology. 2017Mar 1;2:17020
3. Gerstein MB, Rozowsky, Yan KK… Gao G… Waterston R*. Comparative analysis of the transcriptome across distant species. Nature. 2014 Aug 28; 512(7515):445-448.
4. Xue Z, Wu M, Wen K, Ren M, Long L, Zhang X. & Gao G*. CRISPR/Cas9 Mediates Efficient Conditional Mutagenesis in Drosophila. G3:Genes|Genomics| Genetics. 2014 Sep 5. pii: g3.114.014159. (2014 highlight in GSA)
5. Xue Z, Ren M, Wu M, Dai J, Rong YS. & Gao G*. Efficient gene knock-out and knock-in with transgenic Cas9 in Drosophila. G3:Genes|Genomics| Genetics. 2014 Mar 21; 4(5):925-9. (2014 highlight in GSA)
6. Wei W, Xin H, Roy B, Dai J, Miao Y* & Gao G*. Heritable genome editing with CRISPR/Cas9 in the silkworm, Bombyx mori.  PLoS One. 2014 Jul 11; 9(7):e101210.
7. Yu Z#, Ren M#, Wang Z, Zhang B, Rong YS, Jiao R* & Gao G*. Highly efficient genome modifications mediated by CRISPR/Cas9 in Drosophila. Genetics. 2013 Sep; 195(1):289-91. (2013 highlight in GSA)
8. Gao, G. J., Chen, Y., Wesolowska, N. & Rong, YK*. A paternal imprint for the inheritance of telomere identity in Drosophila. PNAS. 2011 Mar 22; 108(12):4932-7.
9. Gao, G. J.,Walse J., Michelle, B., Patrizia, M., Natalia, W., Chen, J. & Rong, YK*. HipHop interacts with HOAP and HP1 to protect Drosophila telomeres in a sequence-independent manner. EMBO J. 2010, Feb 17; 29(4):819-29.
10. Gao, G. J#., Bi, X#., Chen, J., Srikanta, D. & Rong, YK*. Mre11-Rad50-Nbs complex is required to cap telomeres during Drosophila embryogenesis. PNAS. 2009, Jun 30; 106(26):10728-33.
11. Gao, G. J., Conor, M., Chen, J. & Rong, YK*. A powerful method combining homologous recombination and site-specific recombination for targeted mutagenesis in Drosophila. PNAS. 2008, Sep 16; 105(37):13999-4004.
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